{"id":"W2018309238","doi":"10.1002/gps.1746","title":"Efficacy and safety of donepezil over 3 years: an open‐label, multicentre study in patients with Alzheimer's disease","year":2007,"lang":"en","type":"article","venue":"International Journal of Geriatric Psychiatry","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Eisai","keywords":"Donepezil; Placebo; Medicine; Adverse effect; Nausea; Dementia; Clinical Dementia Rating; Open label study; Internal medicine; Clinical trial; Anesthesia; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003044843,0.001430743,0.002536319,0.0004809569,0.0006850467,0.000663001,0.0006379593,0.001107332,0.001064991],"category_scores_gemma":[0.002101417,0.0005651822,0.001655426,0.0004497365,0.0007019871,0.0008707461,0.0004595788,0.001477897,0.0004618506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005349636,"about_ca_system_score_gemma":0.0006478118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009201005,"about_ca_topic_score_gemma":0.001665048,"domain_scores_codex":[0.999054,0.0003892012,0.00009592215,0.0001913288,0.0001580667,0.0001115946],"domain_scores_gemma":[0.998204,0.0003016028,0.0005625235,0.0001644465,0.0001695943,0.0005978722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.761317,0.04285977,0.1177249,0.0008758605,0.00387809,0.0004946113,0.0006742916,0.0008057036,0.01658223,0.00003115999,0.0007807792,0.05397571],"study_design_scores_gemma":[0.2483376,0.3757173,0.368266,0.00006424384,0.001963491,0.0005738029,0.0001279716,0.001018403,0.002394048,0.0000754091,0.001358854,0.0001028209],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982288,0.001011172,0.00009116737,0.00004832973,0.00002792813,0.000201276,0.0001916371,0.00001491657,0.0001846697],"genre_scores_gemma":[0.9980243,0.0004399008,0.0002401528,0.0001732373,0.00009568632,0.0002024134,0.0004971176,0.000004409431,0.0003227433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003044843,"threshold_uncertainty_score":0.01610285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01518932978215371,"score_gpt":0.3515336337989121,"score_spread":0.3363443040167584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}