{"id":"W2018310383","doi":"10.1086/599794","title":"Development of Resistance to Passive Therapy with a Potently Neutralizing Humanized Monoclonal Antibody against West Nile Virus","year":2009,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Virology; Neutralization; Monoclonal antibody; Humanized antibody; Virus; Biology; Epitope; Antibody; Immunotherapy; Neutralizing antibody; West Nile virus; Monoclonal; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004760993,0.0003888123,0.0004636406,0.0001870035,0.0001135268,0.0003374586,0.0002486821,0.0004669921,0.001036466],"category_scores_gemma":[0.0005711883,0.0001428941,0.0003220887,0.0000690981,0.0002244861,0.0002346172,0.0001816409,0.0009706893,0.0002731922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001603144,"about_ca_system_score_gemma":0.00008758547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001466283,"about_ca_topic_score_gemma":0.0001008388,"domain_scores_codex":[0.9997056,0.00008529611,0.00002348981,0.00005224808,0.00005719698,0.00007608782],"domain_scores_gemma":[0.9997079,0.0001200343,0.00005369222,0.00005602763,0.00001946386,0.00004289442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000379363,0.0004588916,0.001062931,0.00003321922,0.00002363992,0.000196047,0.00006291727,0.000114711,0.9908516,0.0001658747,0.0001318723,0.006518962],"study_design_scores_gemma":[0.0003437979,0.02830969,0.01104932,0.00002130383,0.00009558693,0.00643151,0.0000539572,0.003691274,0.9442388,0.0001766561,0.005573399,0.00001479379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968717,0.000531194,0.001560481,0.00007107571,0.00002922228,0.0000604674,0.00006477383,0.00004570766,0.0007654341],"genre_scores_gemma":[0.9979691,0.0002923308,0.0006037845,0.00007480745,0.00001777534,0.00003278635,0.0001498294,0.000009216093,0.00085042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001036466,"threshold_uncertainty_score":0.003467321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009830567767598856,"score_gpt":0.2743389295804507,"score_spread":0.2645083618128519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}