{"id":"W2018345883","doi":"10.1097/01.wcb.0000040948.67415.05","title":"Comparative Evaluation in Nonhuman Primates of Five PET Radiotracers for Imaging the Serotonin Transporters: [ 11 C]McN 5652, [ 11 C]ADAM, [ 11 C]DASB, [ 11 C]DAPA, and [ 11 C]AFM","year":2002,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism","keywords":"Chemistry; Serotonin transporter; Positron emission tomography; In vivo; Pet imaging; Metabolite; Binding potential; Lipophilicity; Nuclear medicine; Serotonin; Stereochemistry; Medicine; Biochemistry; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","scholarly_communication","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","sts"],"category_scores_codex":[0.00586088,0.00375561,0.006003496,0.002977785,0.001833398,0.001573118,0.004947335,0.0009943822,0.002199949],"category_scores_gemma":[0.001193857,0.003280815,0.002752321,0.003387255,0.002802177,0.007290812,0.0004864639,0.003846516,0.000127447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007682474,"about_ca_system_score_gemma":0.00105767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006483296,"about_ca_topic_score_gemma":0.0002697837,"domain_scores_codex":[0.973793,0.004095309,0.007354845,0.003999395,0.00631561,0.004441802],"domain_scores_gemma":[0.9866918,0.002459626,0.003990389,0.002867477,0.002101717,0.001888945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.003065901,0.009257765,0.09535129,0.002021803,0.001678328,0.001851359,0.1564165,0.6163208,0.0876372,0.00138528,0.01031694,0.01469687],"study_design_scores_gemma":[0.04779211,0.002097186,0.02484248,0.002487434,0.009025354,0.005638837,0.01746688,0.749153,0.1101401,0.001101428,0.02396849,0.00628667],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799707,0.003619168,0.0005714204,0.004289062,0.0006637275,0.008613644,0.001654292,0.0003553804,0.0002625959],"genre_scores_gemma":[0.9853339,0.001156259,0.00671037,0.002522645,0.001793431,0.000965781,0.0001739818,0.0006973159,0.0006463759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1389496,"threshold_uncertainty_score":0.9999116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03605536644246025,"score_gpt":0.289164703951819,"score_spread":0.2531093375093588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}