{"id":"W2018398859","doi":"10.1074/jbc.m206902200","title":"Molecular Determinants of Syntaxin 1 Modulation of N-type Calcium Channels","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; University of Calgary; Heart and Stroke Foundation of Canada","keywords":"Voltage-dependent calcium channel; Modulation (music); Chemistry; Calcium; Calcium channel; Syntaxin; L-type calcium channel; Biophysics; Cell biology; Biology; Biochemistry; Physics; Membrane protein; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001592434,0.0001070632,0.0002593737,0.00002008913,0.00001366595,0.000002915271,0.0001582405,0.0002534867,0.000120238],"category_scores_gemma":[0.0000965895,0.00008323965,0.0001904524,0.00007384582,0.00007856739,0.000003427791,0.00002390605,0.00009669593,6.886679e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007292362,"about_ca_system_score_gemma":0.0000157013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000163672,"about_ca_topic_score_gemma":1.478231e-7,"domain_scores_codex":[0.999112,0.00002465045,0.0004823541,0.0001238798,0.000137772,0.00011934],"domain_scores_gemma":[0.9991696,0.000008947073,0.0004095633,0.0001411179,0.000205526,0.00006518787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001162116,0.000106365,0.010796,0.00004934384,0.00002938337,0.00001694619,0.00001393121,0.0001748632,0.9881296,0.000001580303,0.00001478464,0.0005510171],"study_design_scores_gemma":[0.0003190399,0.0003820025,0.002723265,0.00003664361,0.00001970716,0.00006730133,0.00001938785,0.0004631111,0.9952865,0.00003784419,0.0005544952,0.00009068342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966567,0.001117966,0.001900167,0.00001848331,0.00008285622,0.00003851221,0.000006962683,0.000001790171,0.0001765938],"genre_scores_gemma":[0.9992576,0.0002816123,0.0001971541,0.00001356872,0.0001239295,4.931139e-7,0.00006215105,0.000006693982,0.00005674697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008072732,"threshold_uncertainty_score":0.3394414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03149869473036789,"score_gpt":0.2537927340874612,"score_spread":0.2222940393570933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}