{"id":"W2018404810","doi":"10.1016/j.cell.2014.03.005","title":"Remote Control of Gene Function by Local Translation","year":2014,"lang":"en","type":"review","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":315,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Wellcome Trust; Canadian Institutes of Health Research; Ministry of Science, ICT and Future Planning; Autism Speaks","keywords":"Biology; Translation (biology); Gene; Genetics; Function (biology); Computational biology; Evolutionary biology; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008964569,0.0001604571,0.0004013527,0.00002501444,0.00001166716,0.000003614427,0.00008336841,0.0002765849,0.00001092956],"category_scores_gemma":[0.000004294099,0.0001479829,0.0002130657,0.00003673716,0.00002118066,4.329476e-7,0.000006941679,0.00007318546,0.000009476433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000566566,"about_ca_system_score_gemma":0.00003661241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003466853,"about_ca_topic_score_gemma":0.000001200279,"domain_scores_codex":[0.9993397,0.00003667833,0.0002489702,0.0002057118,0.00006062981,0.0001083151],"domain_scores_gemma":[0.9996094,0.00001072898,0.0000960719,0.0002239579,0.00002274761,0.00003707029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007402547,0.000009617634,9.206014e-8,0.002870969,0.00004045049,1.480976e-7,0.000002002549,0.0001151516,0.02927857,5.454363e-7,0.0008813099,0.9667937],"study_design_scores_gemma":[0.000240078,0.0001070491,1.906891e-7,0.0001839896,0.0002627522,0.000002854458,0.000001034347,0.0002432691,0.01952005,0.000001948117,0.9792969,0.0001398441],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00000278459,0.5439432,0.4555161,0.00000104467,0.00008911129,0.0001033924,0.00001906703,0.000003099422,0.0003221322],"genre_scores_gemma":[0.002498617,0.9959309,0.0004206459,0.00001350663,0.0001856227,0.00000460536,0.0005832257,0.00003139082,0.0003314594],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9784156,"threshold_uncertainty_score":0.6034569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00906077590553972,"score_gpt":0.2788775767085215,"score_spread":0.2698168008029818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}