{"id":"W2018482496","doi":"10.1016/j.ijpharm.2004.05.026","title":"Paclitaxel-loaded poly(l-lactic acid) microspheres 3: blending low and high molecular weight polymers to control morphology and drug release","year":2004,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Surgical Specialties (Canada)","funders":"","keywords":"Lactic acid; Microsphere; Paclitaxel; Morphology (biology); Drug; Polymer; Chemistry; Drug carrier; Drug delivery; Materials science; Chemical engineering; Pharmacology; Organic chemistry; Bacteria; Medicine; Surgery; Chemotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006557124,0.0003470399,0.0004738109,0.0003380069,0.0001461265,0.0000682499,0.0004869902,0.0002050545,0.0003348706],"category_scores_gemma":[0.0002092764,0.0003409372,0.0001304021,0.0001621256,0.0002861649,0.0003769475,0.0001496073,0.001024683,0.00004099982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003116471,"about_ca_system_score_gemma":0.0001599489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004216048,"about_ca_topic_score_gemma":0.000005144404,"domain_scores_codex":[0.9975176,0.0003725761,0.000835182,0.0003408249,0.0004512869,0.0004825262],"domain_scores_gemma":[0.9977508,0.0003891943,0.0006161654,0.0001333006,0.0004410506,0.0006694444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002814172,0.0003731667,0.003646893,0.00005898956,0.001530389,0.002698356,0.001211417,0.002485796,0.9430249,0.002002191,0.000475581,0.03967816],"study_design_scores_gemma":[0.01252287,0.0001907058,0.0004099806,0.0001448535,0.0004491809,0.00277703,0.0004477594,0.0005047349,0.9537738,0.0009609701,0.02738024,0.0004378438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9492756,0.02426014,0.01027085,0.01035871,0.005212258,0.0003076738,0.0001473107,0.00003766728,0.0001298567],"genre_scores_gemma":[0.987826,0.001205137,0.001815746,0.008149414,0.0007835766,0.000009515151,0.000006033169,0.00004778044,0.0001567367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03924032,"threshold_uncertainty_score":0.9999043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02676381299766991,"score_gpt":0.3793266778361371,"score_spread":0.3525628648384672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}