{"id":"W2018522439","doi":"10.1016/j.nbd.2009.07.028","title":"Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases","year":2009,"lang":"en","type":"review","venue":"Neurobiology of Disease","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":800,"is_retracted":false,"has_abstract":false,"ca_institutions":"Angiochem (Canada)","funders":"","keywords":"Blood–brain barrier; Transcytosis; Neuroscience; Central nervous system; Receptor; Homeostasis; LRP1; Medicine; Biology; Pharmacology; Cell biology; Internal medicine; Lipoprotein; LDL receptor; Endocytosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05312826422041209,"score_gpt":0.3059656012144333,"score_spread":0.2528373369940212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}