{"id":"W2018554832","doi":"10.1038/srep01867","title":"IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis","year":2013,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Department of Education, Heilongjiang Province","keywords":"CD36; Internalization; Macrophage; Foam cell; Cell biology; Pinocytosis; Phagocytosis; Scavenger receptor; Chemistry; Actin; Receptor; Biology; Biochemistry; Lipoprotein; Cholesterol; In vitro; Endocytosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005971858,0.0002961987,0.0003876612,0.0001103906,0.0006367221,0.0003495449,0.0002726451,0.0002322997,0.005238676],"category_scores_gemma":[0.00008948841,0.0002571392,0.0004181231,0.0002557886,0.0003710039,0.0003468504,0.0001773531,0.0001798385,0.00113913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008242861,"about_ca_system_score_gemma":0.00004093679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001354048,"about_ca_topic_score_gemma":0.00000463857,"domain_scores_codex":[0.9973638,0.0002018355,0.0006930901,0.001011784,0.0002058599,0.0005236177],"domain_scores_gemma":[0.9982039,0.00002332559,0.0004343638,0.001087356,0.0001558259,0.00009521025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001760668,0.00013394,0.00365775,0.0000185015,0.0002029532,0.000005234923,0.0001663357,0.000008893408,0.9784022,0.000004514435,0.0145644,0.002817645],"study_design_scores_gemma":[0.0006692338,0.00002575426,0.01840541,0.00007892639,0.00007964741,0.0001099533,0.0001485187,0.00000605793,0.9623997,0.0003386271,0.0174089,0.0003292581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886636,0.003327853,0.0005171425,0.00006081778,0.00637862,0.000561983,0.00001518133,0.0001987861,0.0002760889],"genre_scores_gemma":[0.9713408,0.0000822525,0.00006661571,0.00003361897,0.00004612403,0.0001264546,0.0002936281,0.00004796399,0.0279625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02768641,"threshold_uncertainty_score":0.9999881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00615210373973455,"score_gpt":0.192197208115915,"score_spread":0.1860451043761804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}