{"id":"W2018554832","doi":"10.1038/srep01867","title":"IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis","year":2013,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Department of Education, Heilongjiang Province","keywords":"CD36; Internalization; Macrophage; Foam cell; Cell biology; Pinocytosis; Phagocytosis; Scavenger receptor; Chemistry; Actin; Receptor; Biology; Biochemistry; Lipoprotein; Cholesterol; In vitro; Endocytosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000138761,0.000297331,0.0002728054,0.0002578427,0.0002257799,0.0002874334,0.000173291,0.0004336523,0.0006335002],"category_scores_gemma":[0.0001125389,0.0001531613,0.0002123088,0.0001554143,0.0003520387,0.0002493005,0.0002489774,0.0007323361,0.0003300442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004598364,"about_ca_system_score_gemma":0.0001688896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003973403,"about_ca_topic_score_gemma":0.0005125399,"domain_scores_codex":[0.9998505,0.00002807292,0.000007731104,0.00002660262,0.00002861353,0.00005846364],"domain_scores_gemma":[0.9999127,0.000006922424,0.00003425239,0.00000727856,0.00001024933,0.00002858003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002577829,0.00002550083,0.0004117556,0.00003886688,0.000002089362,0.00008006796,0.00002582488,0.00004093854,0.9981484,0.00009230245,0.00005760505,0.0008188613],"study_design_scores_gemma":[0.00005469058,0.0003086659,0.04303532,0.00002796272,0.00003348746,0.000398991,0.0001204661,0.00177263,0.9497589,0.0001871554,0.004288581,0.00001316571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953395,0.002442197,0.00091794,0.0001681949,0.00002324713,0.00001878008,0.0001538841,0.00007093263,0.0008653903],"genre_scores_gemma":[0.9956468,0.001168197,0.001045677,0.00008927088,0.00001402705,0.00004169118,0.0002631523,0.00001853729,0.001712745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006335002,"threshold_uncertainty_score":0.00333637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00615210373973455,"score_gpt":0.192197208115915,"score_spread":0.1860451043761804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}