{"id":"W2018560092","doi":"10.1002/ajmg.a.30187","title":"Growth hormone deficiency in Costello syndrome","year":2004,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part A","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; McGill University; SickKids Foundation; Children's Hospital of Western Ontario; University of Toronto; Montreal Children's Hospital","funders":"","keywords":"Costello syndrome; Growth hormone deficiency; Medicine; Endocrinology; Growth hormone; Internal medicine; Hormone; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006058333,0.0001471275,0.0002952556,0.00008807406,0.00002757661,0.00001510583,0.0005462203,0.00009439209,0.00002219556],"category_scores_gemma":[0.000467192,0.0001289338,0.00009820587,0.0002837211,0.000438851,0.000003935773,0.0001327956,0.0002617208,0.000010202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003285989,"about_ca_system_score_gemma":0.0004632472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004401217,"about_ca_topic_score_gemma":0.00001936545,"domain_scores_codex":[0.9981522,0.00007550162,0.0005294088,0.0001957412,0.0007313076,0.0003158524],"domain_scores_gemma":[0.9990161,0.00002188849,0.000289543,0.0002142782,0.0001111004,0.0003471009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003679611,0.008049745,0.1050428,0.0002652119,0.001056807,0.01563816,0.001688119,0.006790095,0.3548933,0.008299548,0.03267269,0.4619239],"study_design_scores_gemma":[0.02168748,0.05025234,0.126507,0.001144373,0.0002791144,0.0237407,0.001479688,0.00009753054,0.6788302,0.005450441,0.08789827,0.002632875],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9706337,0.02480477,0.003097004,0.001140432,0.0001493469,0.00008844818,0.000008056461,0.000003363059,0.00007491746],"genre_scores_gemma":[0.9915906,0.004895066,0.002627351,0.0006987973,0.0001453046,0.000004551551,0.000009335199,0.00001942302,0.000009582782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.459291,"threshold_uncertainty_score":0.5257769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006885404327853248,"score_gpt":0.2546674772671278,"score_spread":0.2477820729392745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}