{"id":"W2018626410","doi":"10.1016/s0959-8049(02)80597-4","title":"Regulation and targets of receptor tyrosine kinases","year":2002,"lang":"en","type":"review","venue":"European Journal of Cancer","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":262,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Autophosphorylation; Cell biology; Receptor tyrosine kinase; Signal transduction; Phosphorylation; SH2 domain; Phosphotyrosine-binding domain; Receptor Protein-Tyrosine Kinases; Biology; Signal transducing adaptor protein; PDZ domain; Tyrosine phosphorylation; Chemistry; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004143309,0.001137705,0.001180985,0.001220447,0.0002657282,0.001246293,0.001001811,0.001120997,0.002116815],"category_scores_gemma":[0.0003914789,0.0003000071,0.0003502851,0.001742899,0.0004815347,0.001234466,0.0005402531,0.001562028,0.001761128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00095483,"about_ca_system_score_gemma":0.0007180876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009992979,"about_ca_topic_score_gemma":0.001770337,"domain_scores_codex":[0.9998232,0.00001785282,0.00002157616,0.00003467013,0.00007597292,0.00002689099],"domain_scores_gemma":[0.9998912,0.00003140553,0.00002467409,0.000005105635,0.00003344026,0.00001417509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002861143,0.0001122506,0.0003465738,0.006728566,0.00009112456,0.000878952,0.00006743421,0.00128388,0.01492321,0.007545572,0.04599087,0.9217455],"study_design_scores_gemma":[0.00002593941,0.00004995206,0.001157196,0.0005101089,0.00006813352,0.001283339,0.00003998169,0.0001556951,0.002246632,0.001585755,0.9928632,0.00001403002],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004578424,0.9965854,0.0003098481,0.0002921742,0.0005288512,0.00000592187,0.00003105162,0.00001293865,0.001775988],"genre_scores_gemma":[0.001908698,0.9947423,0.0003319322,0.000184758,0.0003198972,0.000009865599,0.00005792443,0.000002164297,0.002442516],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002116815,"threshold_uncertainty_score":0.007081509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1000962564019976,"score_gpt":0.3337335402007452,"score_spread":0.2336372837987475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}