{"id":"W2018631466","doi":"10.1128/jvi.01296-09","title":"Application of Bioluminescence Imaging to the Prediction of Lethality in Vaccinia Virus-Infected Mice","year":2009,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Manitoba","funders":"National Institute of Allergy and Infectious Diseases; U.S. Public Health Service; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Vaccinia; Biology; Lethality; Bioluminescence imaging; Bioluminescence; Receiver operating characteristic; Virus; Virology; Spleen; Luciferase; Immunology; Recombinant DNA; Medicine; Internal medicine; Toxicology; Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007151723,0.00007111066,0.0002564524,0.0002133695,0.00003034449,0.000002042256,0.0002746196,0.0001053385,0.00003263226],"category_scores_gemma":[0.0002827996,0.00004961556,0.00006550823,0.0002366279,0.00009717828,0.00007056621,0.00003397791,0.0003255003,0.00001555098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002824615,"about_ca_system_score_gemma":0.000058974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002199083,"about_ca_topic_score_gemma":0.00007107529,"domain_scores_codex":[0.9988423,0.0002944331,0.0005278442,0.00009838636,0.00004587065,0.0001911438],"domain_scores_gemma":[0.9991265,0.000154281,0.0003645368,0.0001622723,0.0001702907,0.00002210157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007194281,0.0001490253,0.02966345,0.000005012601,0.00002431878,0.000002130177,0.0001877043,0.00002530019,0.951252,0.00009187152,0.0004991665,0.01738058],"study_design_scores_gemma":[0.0008335146,0.0006589143,0.6724975,0.00002015413,0.00001620506,0.0001221279,0.00003774422,0.00006166326,0.3219689,0.000206537,0.003541569,0.00003523528],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940563,0.0009793108,0.002181431,0.002347644,0.0001371395,0.0001423498,0.00002453585,0.000004249435,0.0001269849],"genre_scores_gemma":[0.9994833,0.0001420212,0.00005771485,0.0002557639,0.00003922933,0.000002112355,0.000005229691,0.000002886774,0.00001171521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.642834,"threshold_uncertainty_score":0.2023264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009677451504564087,"score_gpt":0.274508156020777,"score_spread":0.264830704516213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}