{"id":"W2018662989","doi":"10.1038/npp.2008.73","title":"Pituitary Adenylate Cyclase-Activating Polypeptide Inhibits Food Intake in Mice Through Activation of the Hypothalamic Melanocortin System","year":2008,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":106,"is_retracted":false,"has_abstract":false,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Centre National de la Recherche Scientifique; Région Normandie; Institut National de la Santé et de la Recherche Médicale","keywords":"Internal medicine; Endocrinology; Melanocortin; Proopiomelanocortin; Hypothalamus; Receptor; Chemistry; Arcuate nucleus; Neuropeptide; Melanocortin receptor; Melanocortin 3 receptor; Biology; Hormone; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000362347,0.00105639,0.0005045237,0.0009742025,0.0003524628,0.0006055234,0.000562416,0.0007954524,0.001805864],"category_scores_gemma":[0.0003203618,0.0005417595,0.000492578,0.0002707374,0.001545621,0.0004750007,0.0003448179,0.002773057,0.0004064867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001042369,"about_ca_system_score_gemma":0.000622401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001460076,"about_ca_topic_score_gemma":0.003098766,"domain_scores_codex":[0.9995636,0.00007221811,0.00002827579,0.0001049005,0.0001044406,0.0001265649],"domain_scores_gemma":[0.9994329,0.00007220012,0.0001864384,0.00006608518,0.00002333045,0.0002189675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001792127,0.0002199105,0.0002395633,0.00003085507,0.00001909691,0.00009878255,0.00001935719,0.0001175223,0.9955164,0.0002585326,0.0001704688,0.001517426],"study_design_scores_gemma":[0.0008679656,0.002420994,0.01043158,0.00002889975,0.00009693217,0.0004135175,0.0001185343,0.002645847,0.9785226,0.000743449,0.003671215,0.00003839942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928856,0.001470727,0.0016475,0.0009629568,0.0001533166,0.00004568456,0.0006198797,0.0003262636,0.001888109],"genre_scores_gemma":[0.9887299,0.00134247,0.002550103,0.0003906241,0.00007010421,0.0001409628,0.0006941886,0.000186498,0.005895162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001805864,"threshold_uncertainty_score":0.007562935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03620341264836746,"score_gpt":0.2684106508344019,"score_spread":0.2322072381860344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}