{"id":"W2018662989","doi":"10.1038/npp.2008.73","title":"Pituitary Adenylate Cyclase-Activating Polypeptide Inhibits Food Intake in Mice Through Activation of the Hypothalamic Melanocortin System","year":2008,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":106,"is_retracted":false,"has_abstract":false,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Centre National de la Recherche Scientifique; Région Normandie; Institut National de la Santé et de la Recherche Médicale","keywords":"Internal medicine; Endocrinology; Melanocortin; Proopiomelanocortin; Hypothalamus; Receptor; Chemistry; Arcuate nucleus; Neuropeptide; Melanocortin receptor; Melanocortin 3 receptor; Biology; Hormone; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001212671,0.0002179529,0.0002885901,0.0001446781,0.0002314093,0.000009189138,0.0004259112,0.0001176931,0.0000431633],"category_scores_gemma":[0.0001856144,0.0001845656,0.0001051939,0.0008215142,0.0002314849,0.0003364216,0.0001247135,0.0004580184,0.00002501915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008684025,"about_ca_system_score_gemma":0.0000753697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003945977,"about_ca_topic_score_gemma":0.0000085777,"domain_scores_codex":[0.9976313,0.0005713487,0.0006066799,0.0005219579,0.000315175,0.0003535701],"domain_scores_gemma":[0.9987553,0.0003951559,0.0004695464,0.00028312,0.0000469385,0.0000499915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001726391,0.0001281167,0.004236099,0.00004271116,0.000005718194,0.00002507305,0.0004371718,0.0005862798,0.9933623,0.0004011959,0.0002011954,0.0004015207],"study_design_scores_gemma":[0.001255029,0.0001344684,0.124736,0.00005712461,0.000006577523,0.000148287,0.00004968279,0.0004679488,0.8723747,0.0000731322,0.0005599541,0.0001370602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936944,0.00001929932,0.00003826865,0.0007327088,0.0008241091,0.0005801996,0.00001248894,0.00008798481,0.004010491],"genre_scores_gemma":[0.9980372,0.0000518395,0.0001017093,0.001478384,0.0001259161,0.00002882511,0.00000149466,0.00003362131,0.0001410718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1209876,"threshold_uncertainty_score":0.7526366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03620341264836746,"score_gpt":0.2684106508344019,"score_spread":0.2322072381860344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}