{"id":"W2018698449","doi":"10.1074/jbc.m304534200","title":"Maturation and Release of Interleukin-1β by Lipopolysaccharide-primed Mouse Schwann Cells Require the Stimulation of P2X7 Receptors","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Cell biology; Stimulation; Receptor; Extracellular; Purinergic receptor; Chemistry; Biology; Biochemistry; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002941048,0.000109672,0.0001900714,0.00001078129,0.00003273689,0.000008552193,0.0001376962,0.0001962983,0.00007464462],"category_scores_gemma":[0.0002306739,0.0000675355,0.00009653235,0.00004738355,0.0001334321,0.000008591619,0.00003581337,0.000148955,2.517372e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009559143,"about_ca_system_score_gemma":0.00004137581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002974124,"about_ca_topic_score_gemma":4.906586e-8,"domain_scores_codex":[0.9991413,0.00006660732,0.0004515426,0.0001258229,0.0001130064,0.0001017491],"domain_scores_gemma":[0.9990896,0.00004408284,0.0005139383,0.0001321734,0.0001600515,0.00006013519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002264884,0.00005361866,0.0005836576,0.00003174725,0.00004443662,0.000001426869,0.00001886079,0.00006832885,0.9970865,0.00001362134,0.001679217,0.0001921346],"study_design_scores_gemma":[0.0003634288,0.0002370783,0.00004838103,0.00003338889,0.0000214167,0.00003087804,0.0001703063,0.00001621671,0.9973441,0.00005852862,0.001599341,0.00007698096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958167,0.003369063,0.0005042122,0.00007113112,0.00005538067,0.00004634646,0.000009362016,0.000002058239,0.0001257373],"genre_scores_gemma":[0.9986023,0.0005505337,0.0004182713,0.0000317605,0.0001046738,8.795608e-7,0.00001726747,0.000006360153,0.0002679633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002818529,"threshold_uncertainty_score":0.2754018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01105742334483396,"score_gpt":0.2331797817287431,"score_spread":0.2221223583839092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}