{"id":"W2018775189","doi":"10.1016/s0896-6273(02)01024-3","title":"Clathrin Adaptor AP2 and NSF Interact with Overlapping Sites of GluR2 and Play Distinct Roles in AMPA Receptor Trafficking and Hippocampal LTD","year":2002,"lang":"en","type":"article","venue":"Neuron","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":440,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Vancouver Hospital and Health Sciences Centre; University of Toronto; University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Canadian Institutes of Health Research; EJLB Foundation","keywords":"AMPA receptor; Internalization; Clathrin; Long-term depression; Cell biology; Endocytosis; Receptor; Signal transducing adaptor protein; Hippocampal formation; Biology; Neuroscience; NMDA receptor; Chemistry; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005039687,0.0001117325,0.0001263836,0.00003355727,0.00002788929,0.00001615025,0.00003174194,0.00007153276,0.000009670332],"category_scores_gemma":[0.00001238575,0.00009968832,0.00001710802,0.00003452691,0.00007006565,0.000007443593,0.00001657443,0.00008720828,2.143674e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003273242,"about_ca_system_score_gemma":0.000004805949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001416511,"about_ca_topic_score_gemma":0.0002207052,"domain_scores_codex":[0.999424,0.00002479273,0.0001305061,0.0002436256,0.00006283278,0.0001142791],"domain_scores_gemma":[0.9997959,0.00001481334,0.00004851339,0.00008384515,0.00001252099,0.00004439876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000160033,0.00003277144,0.09855691,0.00004050364,0.000008464584,0.00000542449,0.0003836479,0.0000103155,0.8961762,0.000007254594,0.00001148594,0.00460696],"study_design_scores_gemma":[0.004285272,0.002610468,0.7733364,0.0003939717,0.00007814835,0.00008423599,0.0005517333,0.004343746,0.1902173,0.00001331342,0.02327611,0.0008092671],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984765,0.001067602,0.0001928689,0.00004650604,0.00002383106,0.00008991891,0.00001213292,0.000005423902,0.0000852127],"genre_scores_gemma":[0.9991575,0.0004780501,0.0001089832,0.00002726754,0.00004642332,0.000002556233,0.0001323705,0.00001123002,0.00003561713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7059589,"threshold_uncertainty_score":0.4065172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009457424227885201,"score_gpt":0.1987434691983445,"score_spread":0.1892860449704593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}