{"id":"W2018775189","doi":"10.1016/s0896-6273(02)01024-3","title":"Clathrin Adaptor AP2 and NSF Interact with Overlapping Sites of GluR2 and Play Distinct Roles in AMPA Receptor Trafficking and Hippocampal LTD","year":2002,"lang":"en","type":"article","venue":"Neuron","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":440,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Vancouver Hospital and Health Sciences Centre; University of Toronto; University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Canadian Institutes of Health Research; EJLB Foundation","keywords":"AMPA receptor; Internalization; Clathrin; Long-term depression; Cell biology; Endocytosis; Receptor; Signal transducing adaptor protein; Hippocampal formation; Biology; Neuroscience; NMDA receptor; Chemistry; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003379184,0.0004440276,0.0004117847,0.0004711532,0.0005573909,0.001003095,0.000682753,0.0005580705,0.001400953],"category_scores_gemma":[0.0004610687,0.0004810147,0.0005775063,0.0003002586,0.0004223071,0.00125055,0.001014595,0.0006463311,0.0005475988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001056122,"about_ca_system_score_gemma":0.0004865113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001525196,"about_ca_topic_score_gemma":0.0025829,"domain_scores_codex":[0.9996885,0.00003530555,0.00002769635,0.00004632324,0.00008496276,0.000117297],"domain_scores_gemma":[0.9997488,0.00003262702,0.00006022891,0.00002946007,0.00005023117,0.0000787855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009515873,0.00003114456,0.001552687,0.00005252035,0.00002801387,0.0003000117,0.00003907942,0.0002071394,0.9923375,0.001631655,0.0001088208,0.002759821],"study_design_scores_gemma":[0.0001540107,0.0002134311,0.07299531,0.00002256814,0.0001219233,0.002490098,0.0003018985,0.006944822,0.9109773,0.001853592,0.003882785,0.00004230688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941128,0.001497957,0.002788251,0.0001208619,0.00003190364,0.000008685382,0.000128365,0.00002945156,0.001281775],"genre_scores_gemma":[0.9943468,0.0007421855,0.001879625,0.00005234644,0.00002822799,0.00002793227,0.0003738577,0.00003127908,0.002517785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001525196,"threshold_uncertainty_score":0.007662714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009457424227885201,"score_gpt":0.1987434691983445,"score_spread":0.1892860449704593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}