{"id":"W2018810533","doi":"10.3816/cbc.2008.n.049","title":"Extended Adjuvant Endocrine Therapy in Breast Cancer: Current Status and Future Directions","year":2008,"lang":"en","type":"review","venue":"Clinical Breast Cancer","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"Juravinski Cancer Centre; University of Toronto; McMaster University","funders":"","keywords":"Letrozole; Medicine; Tamoxifen; Breast cancer; Aromatase inhibitor; Oncology; Interim analysis; Anastrozole; Adjuvant therapy; Internal medicine; Exemestane; Adjuvant; Clinical trial; Randomized controlled trial; Cancer; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001153725,0.0007253306,0.001885064,0.0009756595,0.0001904015,0.001153083,0.001021415,0.00109758,0.003348345],"category_scores_gemma":[0.001145684,0.0002433607,0.0004215837,0.001910552,0.0005108753,0.001254789,0.0006022204,0.00171312,0.001355758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005615577,"about_ca_system_score_gemma":0.001137904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009355654,"about_ca_topic_score_gemma":0.002417607,"domain_scores_codex":[0.9998079,0.00004022067,0.00003003319,0.00003489903,0.00006590244,0.00002110207],"domain_scores_gemma":[0.9994326,0.0003321119,0.0000711567,0.00001392367,0.0001036324,0.00004656301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002090317,0.00008738363,0.0003319001,0.007286369,0.00007574606,0.0002175585,0.00003005783,0.000455189,0.001059652,0.001463259,0.01944631,0.9693375],"study_design_scores_gemma":[0.0001268948,0.0002674959,0.001820422,0.003453923,0.0003228358,0.002095247,0.0001018972,0.0002170514,0.0004030152,0.002283265,0.9888831,0.00002497947],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001081871,0.9990508,0.0001036546,0.0002413688,0.0001412953,0.00000223406,0.000008952712,0.000003700002,0.0003397632],"genre_scores_gemma":[0.0007107187,0.998282,0.0002194462,0.0002321694,0.0002288346,0.000004588055,0.00002025616,9.16627e-7,0.0003010353],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003348345,"threshold_uncertainty_score":0.01120132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0269639738199417,"score_gpt":0.3900944497162928,"score_spread":0.3631304758963511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}