{"id":"W2018891074","doi":"10.1016/s0928-4257(01)00078-x","title":"Multiple regulatory events controlling the expression and localization of utrophin in skeletal muscle fibers: insights into a therapeutic strategy for Duchenne muscular dystrophy","year":2002,"lang":"en","type":"review","venue":"Journal of Physiology-Paris","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; University of Ottawa; Muscular Dystrophy Association","keywords":"Utrophin; Duchenne muscular dystrophy; Dystrophin; Muscular dystrophy; Biology; Cell biology; Neuromuscular junction; mdx mouse; Facioscapulohumeral muscular dystrophy; Skeletal muscle; Gene expression; Gene; Neuroscience; Genetics; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000648968,0.000931664,0.001777497,0.0008485921,0.0002819655,0.001229765,0.001226911,0.001148446,0.001665823],"category_scores_gemma":[0.0003231286,0.0002830985,0.0003612362,0.0009310193,0.0007616165,0.001107963,0.0005429607,0.001508144,0.001496398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007988011,"about_ca_system_score_gemma":0.0007429071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006119229,"about_ca_topic_score_gemma":0.0009562643,"domain_scores_codex":[0.999823,0.00001837947,0.00002529385,0.00004917235,0.00005884952,0.00002533982],"domain_scores_gemma":[0.9998305,0.00006466381,0.00002781196,0.00001073484,0.00004278871,0.00002353436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003853639,0.000104058,0.0004152477,0.005861834,0.00009755418,0.001183731,0.0001112361,0.001018523,0.08702362,0.007165773,0.01172319,0.8849098],"study_design_scores_gemma":[0.0001079569,0.0002973777,0.004131424,0.001162614,0.0002885342,0.004741415,0.0001866228,0.0004300492,0.03606243,0.003862953,0.9486563,0.00007240896],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001348441,0.9946303,0.001755134,0.0003552683,0.0003508585,0.000009176249,0.00003556031,0.00004192274,0.001473303],"genre_scores_gemma":[0.006526024,0.9885851,0.001939905,0.0002776307,0.0002894009,0.00001931496,0.00008371452,0.000006765448,0.002272139],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001777497,"threshold_uncertainty_score":0.005795777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01943657873956842,"score_gpt":0.2798182116864191,"score_spread":0.2603816329468507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}