{"id":"W2018989138","doi":"10.1016/j.jbiotec.2014.09.003","title":"Antibiotic resistance in Pseudomonas aeruginosa biofilms: Towards the development of novel anti-biofilm therapies","year":2014,"lang":"en","type":"review","venue":"Journal of Biotechnology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":344,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Cystic Fibrosis Canada","keywords":"Biofilm; Pseudomonas aeruginosa; Quorum sensing; Antibiotic resistance; Microbiology; Antibiotics; Extracellular polymeric substance; Biology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008518078,0.0008599119,0.001749118,0.001778676,0.0002536674,0.001197929,0.001061797,0.00180538,0.002016335],"category_scores_gemma":[0.001002419,0.0003156815,0.000448756,0.001762577,0.000650797,0.001476001,0.0008600701,0.002335686,0.001239325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006242811,"about_ca_system_score_gemma":0.001124679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000868849,"about_ca_topic_score_gemma":0.001949693,"domain_scores_codex":[0.9997265,0.00003859276,0.00002928002,0.00003775243,0.0001368651,0.00003108112],"domain_scores_gemma":[0.9994367,0.0002502477,0.00008123563,0.00001457041,0.0001629073,0.00005437782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001000093,0.00009526898,0.0001475718,0.01165735,0.00006827886,0.0001699654,0.00004399666,0.0003062171,0.005610853,0.00345609,0.02330651,0.9550379],"study_design_scores_gemma":[0.00003644628,0.0002310675,0.0009552314,0.003335055,0.0001782477,0.001344438,0.00007485262,0.0002538075,0.00251938,0.002481049,0.9885506,0.00003980013],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000904576,0.9990807,0.0001572752,0.000279691,0.0001425929,0.000002287535,0.000006223576,0.000003760292,0.0002370557],"genre_scores_gemma":[0.0006482765,0.9985242,0.0002035071,0.0001661257,0.0001473366,0.000003683898,0.00001090017,8.533924e-7,0.0002950732],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002016335,"threshold_uncertainty_score":0.006745338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0299702387010835,"score_gpt":0.2858423655833584,"score_spread":0.2558721268822749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}