{"id":"W2018991595","doi":"10.1016/j.dnarep.2007.07.009","title":"A critical role for the C-terminus of Nej1 protein in Lif1p association, DNA binding and non-homologous end-joining","year":2007,"lang":"en","type":"article","venue":"DNA repair","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; DNA; Saccharomyces cerevisiae; Non-homologous end joining; DNA repair; C-terminus; DNA-binding protein; Homologous chromosome; Biochemistry; Homologous recombination; Function (biology); Plasma protein binding; Dimer; Cell biology; Binding site; Genetics; Yeast; Gene; Transcription factor; Amino acid; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001364218,0.0001266156,0.0001735356,0.0000596466,0.00008027451,0.00001550337,0.0001255623,0.0002133578,0.000006298505],"category_scores_gemma":[0.001218941,0.0001087734,0.0001097782,0.00009370544,0.00005935626,0.000006143972,0.0001038437,0.00009582403,0.000001576828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004328403,"about_ca_system_score_gemma":0.0000603266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002721862,"about_ca_topic_score_gemma":0.0001011002,"domain_scores_codex":[0.9988523,0.00004697853,0.0003135212,0.0003024258,0.0001399503,0.0003448501],"domain_scores_gemma":[0.9992744,0.0001971348,0.0001162487,0.0002562757,0.00009998181,0.00005591691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001048678,0.00006508495,0.006535708,0.00004488082,0.00004779846,0.00001592525,0.0002211173,0.000001555756,0.9900178,0.0003644335,0.000269364,0.002311482],"study_design_scores_gemma":[0.0006801984,0.0004388722,0.005468994,0.00004544893,0.00002814399,0.00002619932,0.0004229691,0.0005500978,0.9872941,0.0003657657,0.00450535,0.0001738768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997483,0.0002361857,0.0009201107,0.0001934033,0.000106214,0.0005104073,0.00001782141,0.00002847423,0.000504402],"genre_scores_gemma":[0.995161,0.000008391978,0.00388856,0.0001356042,0.0001188204,0.00008767822,0.00001638637,0.00002295043,0.0005605985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004235986,"threshold_uncertainty_score":0.4435651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006941393541032692,"score_gpt":0.2585122849193766,"score_spread":0.2515708913783439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}