{"id":"W2018991595","doi":"10.1016/j.dnarep.2007.07.009","title":"A critical role for the C-terminus of Nej1 protein in Lif1p association, DNA binding and non-homologous end-joining","year":2007,"lang":"en","type":"article","venue":"DNA repair","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; DNA; Saccharomyces cerevisiae; Non-homologous end joining; DNA repair; C-terminus; DNA-binding protein; Homologous chromosome; Biochemistry; Homologous recombination; Function (biology); Plasma protein binding; Dimer; Cell biology; Binding site; Genetics; Yeast; Gene; Transcription factor; Amino acid; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002365493,0.0003604333,0.0002721738,0.0002390565,0.000682394,0.000617088,0.0005564537,0.0008987585,0.00285836],"category_scores_gemma":[0.0004359951,0.0002242818,0.000382445,0.000112862,0.0004263712,0.0007697641,0.0004318184,0.0007460173,0.001432716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007435615,"about_ca_system_score_gemma":0.0004172581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009074282,"about_ca_topic_score_gemma":0.0009087083,"domain_scores_codex":[0.9998997,0.00001289189,0.00001195917,0.00002887121,0.00001793573,0.00002864815],"domain_scores_gemma":[0.9995839,0.0001075096,0.00007415619,0.00004944237,0.00005855596,0.0001265482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002248782,0.00001421708,0.0002003363,0.00004204562,0.000002892766,0.0001908717,0.00001728843,0.00003706598,0.9981158,0.0004234853,0.00005743909,0.0006737376],"study_design_scores_gemma":[0.00002568755,0.00005276702,0.008814753,0.00001325708,0.00001136608,0.001021064,0.00004121655,0.0009949567,0.9842314,0.0002830983,0.00450155,0.000008953884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837896,0.00452467,0.008170174,0.0003993325,0.00007395402,0.00003174565,0.0003963783,0.0001140047,0.002500021],"genre_scores_gemma":[0.9859714,0.0007321629,0.006455572,0.0001402468,0.00003469902,0.00004159271,0.00143254,0.00004605728,0.005145716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00285836,"threshold_uncertainty_score":0.009562194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006941393541032692,"score_gpt":0.2585122849193766,"score_spread":0.2515708913783439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}