{"id":"W2018994558","doi":"10.1038/cddis.2012.41","title":"Emerging concepts: linking hypoxic signaling and cancer metabolism","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Lustgarten Foundation; Wellcome Trust; Amgen; Instituto de Salud Carlos III; Damon Runyon Cancer Research Foundation","keywords":"Programmed cell death; Signal transduction; Cell metabolism; Cell biology; Metabolism; Disease; Cancer research; Cell signaling; Biology; Bioinformatics; Apoptosis; Biochemistry; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002363092,0.0006730324,0.0009157473,0.001604213,0.001068567,0.00542087,0.001270224,0.002296038,0.003372664],"category_scores_gemma":[0.001349652,0.0002910805,0.0005126875,0.001446364,0.006354965,0.006805352,0.002298756,0.005474247,0.0005138936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004390064,"about_ca_system_score_gemma":0.002806576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003880313,"about_ca_topic_score_gemma":0.006298664,"domain_scores_codex":[0.9993752,0.0001759965,0.00003385218,0.00009750557,0.0001739976,0.0001434307],"domain_scores_gemma":[0.9988604,0.0004613162,0.0001090731,0.00005693472,0.0002174348,0.0002948957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004497708,0.0001454528,0.0040254,0.002840197,0.0001476187,0.001497975,0.002059437,0.002566974,0.03011526,0.5675189,0.04252752,0.3461054],"study_design_scores_gemma":[0.00002822029,0.0001888563,0.006297106,0.0009819571,0.00007869968,0.001072366,0.003844807,0.001853225,0.007562925,0.5522064,0.425794,0.00009155636],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01173432,0.8144228,0.01467132,0.1414761,0.005342737,0.00002191707,0.00009931577,0.00009780512,0.01213372],"genre_scores_gemma":[0.1390746,0.8118076,0.006534594,0.02279909,0.01252659,0.00004895151,0.0001134781,0.00003031941,0.007064708],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00542087,"threshold_uncertainty_score":0.03185225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01097326010678513,"score_gpt":0.2637845636727107,"score_spread":0.2528113035659256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}