{"id":"W2019110326","doi":"10.1164/rccm.201302-0219oc","title":"Lung Clearance Index as an Outcome Measure for Clinical Trials in Young Children with Cystic Fibrosis. A Pilot Study Using Inhaled Hypertonic Saline","year":2013,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":153,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Medicine; Hypertonic saline; Cystic fibrosis; Confidence interval; Randomized controlled trial; Anesthesia; Clinical trial; Saline; Pediatrics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.006971251,0.0003236022,0.002472601,0.0004078717,0.0001209338,0.00004830372,0.0002208089,0.00006494093,0.00006557567],"category_scores_gemma":[0.02689486,0.0002011638,0.0001460024,0.0005154074,0.001563772,0.0003578361,0.00004418127,0.0009306438,0.000001294912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001488356,"about_ca_system_score_gemma":0.0004475004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000418603,"about_ca_topic_score_gemma":0.0001271505,"domain_scores_codex":[0.9935289,0.002114199,0.002290723,0.0004671287,0.001072634,0.0005263929],"domain_scores_gemma":[0.9932947,0.003516124,0.0005649449,0.0003609245,0.0013343,0.0009289621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01615024,0.0008177804,0.9507754,0.0002068962,0.0001984438,0.0002324872,0.0004924395,0.000009106223,0.002983318,0.00002376955,0.00004183183,0.02806829],"study_design_scores_gemma":[0.01437244,0.1320428,0.8397822,0.001152777,0.0007617847,0.001004804,0.01026802,0.0002467758,0.0000315686,0.00004611062,0.0000470788,0.0002436056],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897767,0.005463212,0.002043068,0.0008331322,0.000131828,0.001705733,0.00001025833,0.00001715381,0.00001890303],"genre_scores_gemma":[0.9957693,0.00003574846,0.002335961,0.0009033338,0.0008496567,0.00004999294,0.000003222522,0.00004997616,0.000002825835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.131225,"threshold_uncertainty_score":0.981302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1096806389900815,"score_gpt":0.4648255957442951,"score_spread":0.3551449567542136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}