{"id":"W2019143048","doi":"10.3858/emm.2011.43.2.010","title":"Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the expression of β-catenin, leading to a rapid proliferation of pancreatic cells","year":2011,"lang":"en","type":"article","venue":"Experimental & Molecular Medicine","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Pusan National University","keywords":"Phosphorylation; Catenin; Pancreatic cancer; Cancer research; Small hairpin RNA; Protein kinase B; Cyclin D1; Signal transduction; Cell growth; Cell biology; Biology; Oncogene; Wnt signaling pathway; Cell cycle; Chemistry; Cell; Cell culture; Gene knockdown; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001071784,0.0004049219,0.0002495145,0.000364325,0.0001526268,0.0002293304,0.0001055645,0.0002429936,0.001671704],"category_scores_gemma":[0.0000997168,0.0001400006,0.0003318248,0.0002466111,0.0001916017,0.0002022154,0.0002018032,0.0007695287,0.0003531084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002355069,"about_ca_system_score_gemma":0.0001938461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004896498,"about_ca_topic_score_gemma":0.0006975539,"domain_scores_codex":[0.9998507,0.00001741531,0.00001506936,0.00003375707,0.00005392657,0.00002912763],"domain_scores_gemma":[0.9999175,0.00001530209,0.00002157496,0.0000104724,0.000008651338,0.00002637623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003377933,0.00001917051,0.0001130473,0.00002402582,0.000002925556,0.00004124864,0.00000778203,0.00001520429,0.9989397,0.00005218416,0.00002372746,0.0007271125],"study_design_scores_gemma":[0.000009056402,0.0002620423,0.003079058,0.000004411264,0.0000121582,0.0003658023,0.0000190019,0.0003529102,0.9927509,0.00002793357,0.003113777,0.00000290904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906777,0.002756849,0.003813935,0.000152239,0.00005580299,0.00004868704,0.0005677278,0.0001517988,0.001775266],"genre_scores_gemma":[0.9875038,0.002044091,0.004726248,0.00007404444,0.00001736861,0.00005900811,0.001038096,0.00002330821,0.004514002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001671704,"threshold_uncertainty_score":0.005592406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01839921326052698,"score_gpt":0.2697207088798973,"score_spread":0.2513214956193703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}