{"id":"W2019315586","doi":"10.1021/tx050095o","title":"A Comparison of the Covalent Binding of Clozapine, Procainamide, and Vesnarinone to Human Neutrophils in Vitro and Rat Tissues in Vitro and in Vivo","year":2005,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"In vitro; Procainamide; In vivo; Clozapine; Pharmacology; Chemistry; Covalent bond; Biochemistry; Internal medicine; Medicine; Biology; Schizophrenia (object-oriented programming); Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006287462,0.0001100953,0.0003800328,0.0004937831,0.00003349953,0.00001486487,0.0002558907,0.0001342375,0.000007200341],"category_scores_gemma":[0.001171822,0.00009365649,0.00001437176,0.000818269,0.000823923,0.00006618409,0.0004662559,0.0005375209,4.967984e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001148368,"about_ca_system_score_gemma":0.00004671344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007308099,"about_ca_topic_score_gemma":0.0003590875,"domain_scores_codex":[0.9981228,0.0003369738,0.000408141,0.0004143406,0.0002469212,0.0004708502],"domain_scores_gemma":[0.9989311,0.0007424133,0.00005311974,0.0001589695,0.00001976648,0.00009462737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006722205,0.0003812331,0.01055945,0.0001126956,7.456735e-7,0.00001285035,0.0009518884,0.00001203602,0.9842403,0.0002146449,0.00002882531,0.002813118],"study_design_scores_gemma":[0.001561553,0.000154761,0.01359964,0.00007516029,5.334795e-7,0.000005313056,0.0002395354,0.0005060262,0.9831805,0.0004118363,0.0001875199,0.00007764174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966074,0.0003451135,4.031211e-7,0.002236863,0.00001369532,0.0006083317,0.000005116885,0.000004062231,0.0001790445],"genre_scores_gemma":[0.9995608,0.0001174482,0.0001097731,0.0001086377,0.00001175896,0.0000557541,5.318734e-7,0.000008873734,0.00002639563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003040195,"threshold_uncertainty_score":0.3819201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1060993963270474,"score_gpt":0.4203702081701297,"score_spread":0.3142708118430823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}