{"id":"W2019315586","doi":"10.1021/tx050095o","title":"A Comparison of the Covalent Binding of Clozapine, Procainamide, and Vesnarinone to Human Neutrophils in Vitro and Rat Tissues in Vitro and in Vivo","year":2005,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"In vitro; Procainamide; In vivo; Clozapine; Pharmacology; Chemistry; Covalent bond; Biochemistry; Internal medicine; Medicine; Biology; Schizophrenia (object-oriented programming); Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001514219,0.0004534019,0.0001527545,0.0002211099,0.0001178896,0.0001633377,0.0001273244,0.0002152848,0.000754894],"category_scores_gemma":[0.0002048734,0.000156655,0.0001966087,0.0001019235,0.0001711821,0.0001378994,0.000121789,0.0002427052,0.00019006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001840003,"about_ca_system_score_gemma":0.0001234281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009547304,"about_ca_topic_score_gemma":0.001417472,"domain_scores_codex":[0.9998322,0.00005166399,0.00001125426,0.00003273026,0.00004000169,0.00003212932],"domain_scores_gemma":[0.9998599,0.00002990493,0.00004681353,0.00002168287,0.00002019979,0.00002145715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008838732,0.000009878572,0.0003783949,0.00002255925,0.000009741386,0.00005067251,0.00001320191,0.00002205277,0.9984622,0.00001498262,0.000004052832,0.0009238818],"study_design_scores_gemma":[0.000007626234,0.0007326713,0.01505075,0.000003601667,0.00003036179,0.0004996911,0.00003345564,0.00026741,0.9825119,0.00001254486,0.0008468819,0.000003209312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934406,0.002497522,0.00285513,0.00002814119,0.00001036235,0.00002211393,0.00006741939,0.00002494384,0.001053848],"genre_scores_gemma":[0.9941778,0.001612094,0.00244879,0.00002984533,0.000008814871,0.00002117334,0.0002544922,0.000006090662,0.001440924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009547304,"threshold_uncertainty_score":0.002525389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1060993963270474,"score_gpt":0.4203702081701297,"score_spread":0.3142708118430823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}