{"id":"W2019316759","doi":"10.1016/j.jpain.2014.07.008","title":"Opioid Selective Antinociception Following Microinjection Into the Periaqueductal Gray of the Rat","year":2014,"lang":"en","type":"article","venue":"Journal of Pain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Purdue Pharma (Canada)","funders":"","keywords":"Buprenorphine; Periaqueductal gray; Morphine; Oxycodone; Microinjection; Opioid; Pharmacology; Methadone; Fentanyl; Medicine; Nociception; Analgesic; μ-opioid receptor; Anesthesia; Receptor; Internal medicine; Central nervous system; Midbrain","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120994,0.0005607784,0.0003736937,0.0004990085,0.0002693608,0.0002774685,0.0003095601,0.0005278136,0.002926818],"category_scores_gemma":[0.000148102,0.0002513962,0.0001741545,0.0002324332,0.0007895236,0.0004530082,0.0001840813,0.0009885187,0.0003078822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004347101,"about_ca_system_score_gemma":0.0007124328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003447729,"about_ca_topic_score_gemma":0.007525115,"domain_scores_codex":[0.9998686,0.000009934294,0.000003891802,0.00002011469,0.00002426475,0.00007310604],"domain_scores_gemma":[0.9998568,0.00001739155,0.00003597881,0.00001477954,0.00001508035,0.00005979386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00212466,0.0003277651,0.0003787315,0.00007377307,0.00001558309,0.0001472248,0.00006512717,0.00008928381,0.9920354,0.0005412867,0.0001167001,0.004084412],"study_design_scores_gemma":[0.0003301122,0.007472503,0.01314736,0.00004562577,0.00006626303,0.0002981192,0.0002499913,0.001299499,0.9753058,0.0005389147,0.001226334,0.00001951184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974709,0.0005316698,0.0004853025,0.0002502063,0.00004038703,0.00001956115,0.000128284,0.00004496754,0.001028769],"genre_scores_gemma":[0.993874,0.0009554099,0.0009480585,0.0001424681,0.00002602385,0.00003587789,0.0001652848,0.0000160398,0.00383684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003447729,"threshold_uncertainty_score":0.009791195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005343755970837709,"score_gpt":0.2487320607155226,"score_spread":0.2433883047446849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}