{"id":"W2019330676","doi":"10.1158/1538-7445.am2014-196","title":"Abstract 196: Targeting breast cancer stem cells with a panel of potential ALDH1A3 inhibitors","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Aldehyde dehydrogenase; Cancer research; Breast cancer; Retinoic acid; Cancer; Medicine; Cancer stem cell; Stem cell; Biology; Internal medicine; Gene; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009931151,0.000483725,0.000337588,0.0004700717,0.0001997731,0.0003385305,0.0002868951,0.0003347477,0.008262696],"category_scores_gemma":[0.00006326864,0.00011508,0.0002911318,0.0003139683,0.00009937175,0.0001597869,0.0001681304,0.0004561809,0.001707265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002631766,"about_ca_system_score_gemma":0.0002900809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009152187,"about_ca_topic_score_gemma":0.002171268,"domain_scores_codex":[0.9999464,0.000005159393,0.000005859515,0.000009179938,0.00002138293,0.00001217483],"domain_scores_gemma":[0.9999732,0.000003256824,0.000005256545,0.000001888183,0.000008072501,0.00000834201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001040053,0.0003112138,0.0004735285,0.0007746133,0.00004129317,0.0002775685,0.00002788472,0.0004418063,0.935573,0.000365503,0.008165689,0.05250784],"study_design_scores_gemma":[0.0002958534,0.003050782,0.005420459,0.00009453507,0.0001348206,0.000907596,0.00002702301,0.0004636327,0.9059362,0.0001187127,0.08352846,0.00002198575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7374879,0.1555497,0.009429032,0.004035994,0.003780567,0.001180866,0.01323271,0.001385779,0.07391743],"genre_scores_gemma":[0.7891569,0.08435356,0.01097362,0.002056841,0.0005273319,0.0004417589,0.0095897,0.0001332314,0.102767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008262696,"threshold_uncertainty_score":0.02764148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02478123936541459,"score_gpt":0.3061475033460602,"score_spread":0.2813662639806456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}