{"id":"W2019354379","doi":"10.3109/15376516.2013.774079","title":"Safety and pharmacokinetic studies of liposomal antioxidant formulations containing N-acetylcysteine,<b>α</b>-tocopherol or<b>γ</b>-tocopherol in beagle dogs","year":2013,"lang":"en","type":"article","venue":"Toxicology Mechanisms and Methods","topic":"Antioxidant Activity and Oxidative Stress","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nucro Technics; NOSM University; Lakehead University","funders":"","keywords":"Beagle; Pharmacokinetics; Acetylcysteine; Pharmacology; Tocopherol; Chemistry; Liposome; Toxicity; Antidote; Medicine; Antioxidant; Vitamin E; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007470153,0.000344928,0.0006069376,0.0003718442,0.0001849025,0.0004287378,0.0003225819,0.0005508339,0.0003218999],"category_scores_gemma":[0.0008685254,0.000242838,0.0003288798,0.0002766784,0.0006137866,0.0006345689,0.0001183072,0.0006430038,0.0001674676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004654149,"about_ca_system_score_gemma":0.0003788683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008438186,"about_ca_topic_score_gemma":0.0006872084,"domain_scores_codex":[0.9995412,0.0001490276,0.00004329951,0.0001018556,0.0001188919,0.00004577598],"domain_scores_gemma":[0.9993879,0.00008791601,0.0002660749,0.00005716267,0.00009934827,0.0001016162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03037433,0.003301105,0.00687734,0.0003316345,0.0002178057,0.0003112998,0.0003314107,0.001467714,0.9338451,0.0002546907,0.0004766171,0.02221079],"study_design_scores_gemma":[0.002995272,0.234979,0.04102949,0.00006141024,0.000937996,0.001835795,0.0004489706,0.007418444,0.6993835,0.0003205555,0.01049869,0.00009080711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980372,0.0006729491,0.0008087979,0.00006254532,0.00001234663,0.00006265745,0.0001274028,0.00002664666,0.0001893607],"genre_scores_gemma":[0.9962274,0.001201948,0.001409024,0.0000763188,0.00002637283,0.0001020924,0.0004016611,0.00001207075,0.0005430353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008438186,"threshold_uncertainty_score":0.003950596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05338282724958652,"score_gpt":0.4046014942120477,"score_spread":0.3512186669624612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}