{"id":"W2019416118","doi":"10.1159/000339541","title":"Safety Verification Trials of mFOLFIRI and Sequential IRIS + Bevacizumab as First- or Second-Line Therapies for Metastatic Colorectal Cancer in Japanese Patients","year":2012,"lang":"en","type":"article","venue":"Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"Bevacizumab; Medicine; Irinotecan; Colorectal cancer; Clinical endpoint; Internal medicine; Gastroenterology; Cancer; Randomized controlled trial; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005551082,0.0001447157,0.0008519804,0.00009149658,0.00006707964,0.000003602339,0.0000355839,0.00008402572,0.0009277079],"category_scores_gemma":[0.0004623993,0.00009598517,0.00008728351,0.0001136683,0.0001103987,0.00007532744,0.00002782355,0.00006347016,0.00000226617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003698142,"about_ca_system_score_gemma":0.0001910374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004848945,"about_ca_topic_score_gemma":0.004403935,"domain_scores_codex":[0.9987885,0.0001407906,0.0005479013,0.0001820395,0.0001078591,0.0002329501],"domain_scores_gemma":[0.9987444,0.0007027864,0.0002735791,0.00008467081,0.0001256268,0.00006896171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1566343,0.01071022,0.2960935,0.001465611,0.005332618,0.00002912167,0.08569234,0.00002091488,0.01404467,0.0003849871,0.003331476,0.4262602],"study_design_scores_gemma":[0.05376297,0.03055779,0.7612091,0.0001695799,0.002067091,0.00005192339,0.005369984,0.0001288149,0.009099927,0.0001976409,0.1369467,0.0004384863],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930609,0.003415113,0.00000861743,0.0008768596,0.0004048405,0.00147038,0.0003061113,0.00001023442,0.0004469236],"genre_scores_gemma":[0.9969761,0.001258322,0.0004239525,0.0001191587,0.0001167256,0.0006413453,0.00008092883,0.00001432026,0.0003691128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4651155,"threshold_uncertainty_score":0.9999856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07763316990562652,"score_gpt":0.400858722084798,"score_spread":0.3232255521791715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}