{"id":"W2019416118","doi":"10.1159/000339541","title":"Safety Verification Trials of mFOLFIRI and Sequential IRIS + Bevacizumab as First- or Second-Line Therapies for Metastatic Colorectal Cancer in Japanese Patients","year":2012,"lang":"en","type":"article","venue":"Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"Bevacizumab; Medicine; Irinotecan; Colorectal cancer; Clinical endpoint; Internal medicine; Gastroenterology; Cancer; Randomized controlled trial; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003836368,0.0009419592,0.002012075,0.0003411835,0.0003980197,0.0005230605,0.0006805327,0.001111197,0.003001699],"category_scores_gemma":[0.002338693,0.0004165664,0.001896491,0.0003983655,0.000965736,0.0005657975,0.000380986,0.001334801,0.0003298205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001278969,"about_ca_system_score_gemma":0.002570688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001509628,"about_ca_topic_score_gemma":0.004197007,"domain_scores_codex":[0.9984241,0.000968913,0.0001731368,0.0001866212,0.0001453818,0.0001019253],"domain_scores_gemma":[0.9979299,0.0003576897,0.0008970342,0.0001477584,0.000186802,0.0004808134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8951709,0.009560465,0.006575498,0.001643595,0.00352183,0.0000813922,0.000250351,0.0006587991,0.009445762,0.0001421947,0.0006181298,0.07233105],"study_design_scores_gemma":[0.5181992,0.4484933,0.02067114,0.0001257053,0.004704586,0.0002285928,0.000100954,0.0008402711,0.003594206,0.0001214015,0.002888894,0.00003162906],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885727,0.007796041,0.0004970142,0.0003795727,0.00008727684,0.001380846,0.0002388592,0.00003036076,0.001017223],"genre_scores_gemma":[0.9928965,0.003078766,0.00119807,0.0004061769,0.0001619328,0.001219196,0.0004097426,0.000006614642,0.0006230877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003836368,"threshold_uncertainty_score":0.02028888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07763316990562652,"score_gpt":0.400858722084798,"score_spread":0.3232255521791715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}