{"id":"W2019458490","doi":"10.1091/mbc.11.1.141","title":"Mutants of the<i>Yarrowia lipolytica PEX23</i>Gene Encoding an Integral Peroxisomal Membrane Peroxin Mislocalize Matrix Proteins and Accumulate Vesicles Containing Peroxisomal Matrix and Membrane Proteins","year":2000,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Yarrowia; Peroxisome; Biology; Peroxisomal targeting signal; Biochemistry; Saccharomyces cerevisiae; Microbody; Membrane protein; Complementation; Protein targeting; Mutant; Fungal protein; Yeast; Cell biology; Gene; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001188282,0.001141488,0.0002638579,0.0002957529,0.0002396711,0.0003772349,0.0004160982,0.0003225807,0.001309562],"category_scores_gemma":[0.0001395156,0.0002494553,0.0004021958,0.0003448517,0.0003566016,0.0002012535,0.0004862114,0.0005159592,0.001267047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004476955,"about_ca_system_score_gemma":0.0002215467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001206239,"about_ca_topic_score_gemma":0.001192492,"domain_scores_codex":[0.9998641,0.00001699314,0.0000159755,0.00003173186,0.00004160809,0.00002955868],"domain_scores_gemma":[0.9997944,0.00002527384,0.00008662323,0.00002471226,0.00001665402,0.00005230966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005989357,0.00001683608,0.000124581,0.00001873953,0.000008487896,0.00009443993,0.000009201513,0.00005028618,0.9990174,0.000107919,0.0000415838,0.000450659],"study_design_scores_gemma":[0.00002954528,0.0001395427,0.005547309,0.000007925991,0.00002672256,0.0009344361,0.0000398002,0.0006599585,0.9882725,0.000081286,0.004248423,0.00001251045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890126,0.0007935736,0.005989586,0.0001097341,0.00004627651,0.00005884243,0.001689988,0.0003025149,0.001996779],"genre_scores_gemma":[0.9784067,0.0007962795,0.005612133,0.00006442005,0.00001537367,0.000110284,0.004910749,0.0002448485,0.009839278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001309562,"threshold_uncertainty_score":0.004380941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007555174404315782,"score_gpt":0.2538715300059597,"score_spread":0.246316355601644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}