{"id":"W2019507798","doi":"10.1074/jbc.m109.029538","title":"Bin1 Src Homology 3 Domain Acts as a Scaffold for Myofiber Sarcomere Assembly","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences; Ottawa Hospital; Stem Cell Network","funders":"Canadian Institutes of Health Research; Muscular Dystrophy Association; Heart and Stroke Foundation of Canada","keywords":"Sarcomere; Myocyte; Scaffold; Proto-oncogene tyrosine-protein kinase Src; Cell biology; Chemistry; Scaffold protein; Homology (biology); Biophysics; Biology; Biochemistry; Phosphorylation; Amino acid; Signal transduction; Medicine; Biomedical engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001004648,0.0002790651,0.0001830441,0.0001910041,0.0003189423,0.0003386479,0.0002220617,0.0002377298,0.002173428],"category_scores_gemma":[0.0001158309,0.0001389674,0.0001870304,0.0001475809,0.0001770479,0.0002948767,0.0003440124,0.000278123,0.0009212322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004619014,"about_ca_system_score_gemma":0.0001555487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005571749,"about_ca_topic_score_gemma":0.001166406,"domain_scores_codex":[0.9999124,0.000009974258,0.000004307602,0.00002297717,0.00002692891,0.00002342011],"domain_scores_gemma":[0.9999242,0.00001040659,0.00002216757,0.000006064067,0.000008092995,0.00002907143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001854774,0.00001447382,0.00146636,0.00008314484,0.000009979318,0.0001701986,0.00002623559,0.0002207558,0.994132,0.0004964661,0.0001484284,0.003046527],"study_design_scores_gemma":[0.00002527415,0.0001318345,0.04019761,0.00001195885,0.00003024885,0.001523149,0.00007353951,0.004862288,0.9427653,0.0004525984,0.00991101,0.00001517434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883544,0.002957593,0.005445405,0.0001056458,0.00002773879,0.00001486051,0.0003128421,0.0001923088,0.002589266],"genre_scores_gemma":[0.9950062,0.0004806474,0.001841543,0.00002857774,0.000005706702,0.000006537627,0.0004793437,0.00001636574,0.002135058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002173428,"threshold_uncertainty_score":0.007270813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01475598554988377,"score_gpt":0.2755100619848843,"score_spread":0.2607540764350005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}