{"id":"W2019530604","doi":"10.1093/nar/gkg742","title":"Retrovirus silencer blocking by the cHS4 insulator is CTCF independent","year":2003,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Stem Cell Network","keywords":"Silencer; CTCF; Retrovirus; Gene silencing; Biology; Transgene; Hypersensitive site; Insulator (electricity); Molecular biology; Enhancer; Genetics; Gene; Gene expression; Materials science; Optoelectronics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004721837,0.0003713727,0.0003133403,0.0003738569,0.0001899542,0.0004933752,0.0003090842,0.0002228435,0.001407641],"category_scores_gemma":[0.0002711084,0.0002625768,0.0003843813,0.0001651955,0.0005361696,0.0002167734,0.0004112625,0.0007754287,0.0005922001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005062169,"about_ca_system_score_gemma":0.0003919568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005869452,"about_ca_topic_score_gemma":0.001256112,"domain_scores_codex":[0.9994102,0.00009454502,0.00004116304,0.00007579349,0.0003010583,0.00007719837],"domain_scores_gemma":[0.9994186,0.000168752,0.0001696841,0.0001084865,0.00006847926,0.00006599569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001505456,0.000009260149,0.000153267,0.00001313522,0.000003327802,0.00001387119,0.00000737871,0.00002992556,0.9985886,0.0001877859,0.00001831461,0.0009601056],"study_design_scores_gemma":[0.00000616801,0.00007996555,0.001017103,0.000002654106,0.000005494958,0.0001254001,0.000006881568,0.0005222134,0.9969201,0.00005540763,0.001256541,0.000002088437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9619329,0.001151087,0.03097485,0.0001912816,0.00003646123,0.00009550068,0.0002304311,0.0004264823,0.004961014],"genre_scores_gemma":[0.980545,0.00060029,0.01275457,0.00006213594,0.00001471385,0.0000739955,0.0007042379,0.00009859225,0.00514634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001407641,"threshold_uncertainty_score":0.004709065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02239032529390379,"score_gpt":0.3030623724794098,"score_spread":0.280672047185506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}