{"id":"W2019577645","doi":"10.1074/jbc.m604252200","title":"Fer and Fps/Fes Participate in a Lyn-dependent Pathway from FcϵRI to Platelet-Endothelial Cell Adhesion Molecule 1 to Limit Mast Cell Activation","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Cancer Institute; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"LYN; FYN; Degranulation; Syk; Mast cell; Cell biology; Phosphorylation; Kinase; Chemistry; Proto-oncogene tyrosine-protein kinase Src; Tyrosine phosphorylation; Tyrosine kinase; Protein tyrosine phosphatase; Receptor; Molecular biology; Signal transduction; Biology; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001312478,0.0004256629,0.0001540343,0.0001364763,0.0001896536,0.0002902433,0.0002042937,0.0002585972,0.0008394455],"category_scores_gemma":[0.0001114489,0.0001109625,0.0002595173,0.00006245149,0.0001316472,0.0003386669,0.0002934324,0.0003918923,0.0002871956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003208175,"about_ca_system_score_gemma":0.000173511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005589616,"about_ca_topic_score_gemma":0.0004037624,"domain_scores_codex":[0.9998891,0.00001062508,0.000005950659,0.00002170246,0.00003083017,0.0000416774],"domain_scores_gemma":[0.9999603,0.000003616264,0.00001213697,0.000002440092,0.000007139005,0.00001433122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001538429,0.00001478888,0.0002825311,0.00003904398,0.000005350094,0.0001828591,0.00002799938,0.00009659111,0.9963948,0.0005227108,0.00006672517,0.00221278],"study_design_scores_gemma":[0.00004786385,0.0002738152,0.0224636,0.00001744511,0.00002878484,0.001154291,0.00008657805,0.002642083,0.9651796,0.0004161374,0.007676295,0.00001354781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863836,0.004498139,0.00555879,0.0001650426,0.00002972319,0.0000486359,0.0002187183,0.00008574949,0.003011763],"genre_scores_gemma":[0.9931566,0.0008975561,0.002402736,0.00005121476,0.00001348945,0.00002977904,0.00033989,0.000005991687,0.003102728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008394455,"threshold_uncertainty_score":0.002808213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01511313255552335,"score_gpt":0.2106866248549966,"score_spread":0.1955734922994733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}