{"id":"W2019582232","doi":"10.1159/000117715","title":"Spatial Distribution of Histone Isoforms on the Bovine Active and Inactive X Chromosomes","year":2008,"lang":"en","type":"article","venue":"Sexual Development","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; X chromosome; Histone; Heterochromatin; Molecular biology; Constitutive heterochromatin; X-inactivation; Histone H3; Histone H2A; Histone H1; Autosome; Gene isoform; Replication timing; Dosage compensation; Heterochromatin protein 1; Chromosome; Genetics; Chromatin; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001093695,0.0001126739,0.0001415764,0.0004878999,0.0001636219,0.0003445177,0.0001418856,0.0001732788,0.001099952],"category_scores_gemma":[0.0001018403,0.0001429492,0.0001247987,0.0002526413,0.0001824137,0.0001746914,0.0001907102,0.0001888146,0.0002783307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001585704,"about_ca_system_score_gemma":0.00008134228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001802116,"about_ca_topic_score_gemma":0.002196541,"domain_scores_codex":[0.9998933,0.00001067828,0.000008344971,0.00004000028,0.00002565916,0.00002198984],"domain_scores_gemma":[0.9998615,0.00002803123,0.00004150826,0.00001416621,0.00002261703,0.00003215173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001078211,0.000003763647,0.003094197,0.00002694033,0.00000587044,0.00005596062,0.00006334991,0.00001686071,0.9953615,0.00007608692,0.000009565282,0.001178168],"study_design_scores_gemma":[0.0000308795,0.0004907712,0.601494,0.00003959226,0.00008008373,0.00178226,0.0005879311,0.0006444179,0.3878254,0.0001497429,0.00685446,0.00002049001],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930634,0.00339417,0.001655753,0.00001926715,0.000006987155,0.000004608043,0.0002072773,0.00001449482,0.001634134],"genre_scores_gemma":[0.9957632,0.00117122,0.001004227,0.00002238526,0.000008546149,0.000007190782,0.0004309767,0.000007933128,0.00158417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001802116,"threshold_uncertainty_score":0.003679693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01674728093735264,"score_gpt":0.2682504811160773,"score_spread":0.2515032001787247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}