{"id":"W2019689022","doi":"10.1016/j.cbi.2011.02.027","title":"Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde","year":2011,"lang":"en","type":"article","venue":"Chemico-Biological Interactions","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Glycolaldehyde; Glyceraldehyde; Glyoxal; Chemistry; Protein Carbonylation; Autoxidation; Biochemistry; Cytotoxicity; Glutathione; Organic chemistry; Dehydrogenase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002523705,0.0004461001,0.0001491695,0.0003361579,0.0002041862,0.0003024404,0.0003391372,0.0004070712,0.002535236],"category_scores_gemma":[0.0001401769,0.0001926086,0.0002643908,0.0001750776,0.0004310324,0.0004946304,0.0001963411,0.0003702073,0.0002387733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003237357,"about_ca_system_score_gemma":0.0001579017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005170142,"about_ca_topic_score_gemma":0.0004178115,"domain_scores_codex":[0.9999229,0.00002110039,0.00000512028,0.00001004609,0.00001375978,0.00002709307],"domain_scores_gemma":[0.9999084,0.00002763763,0.00001888703,0.00001883397,0.00001373167,0.00001259049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002420655,0.000167204,0.001948825,0.0002143061,0.00004530028,0.0004808915,0.00009135422,0.0004277217,0.9812607,0.003943568,0.0001198784,0.008879638],"study_design_scores_gemma":[0.00005653232,0.0008852551,0.01017054,0.00001332867,0.00004608879,0.0004727741,0.00007497649,0.000531049,0.9850664,0.0008838414,0.001793526,0.000005775856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812698,0.01162601,0.002841526,0.0003296017,0.00005697738,0.0000505018,0.0002474622,0.00007818068,0.00349994],"genre_scores_gemma":[0.9964367,0.001669138,0.0002788011,0.00004348362,0.00001517116,0.00001194124,0.0001122715,0.000003823252,0.001428563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002535236,"threshold_uncertainty_score":0.008481145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1262035145875974,"score_gpt":0.3594312478520308,"score_spread":0.2332277332644335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}