{"id":"W2019693087","doi":"10.1159/000341450","title":"Ubiquitin E3 Ligase A20 Contributes to Maintaining Epithelial Barrier Function","year":2012,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Science and Technology Commission of Shanghai Municipality; Institute of Engineering Research, Seoul National University; National Natural Science Foundation of China","keywords":"Cell biology; Endosome; Endocytic cycle; Endocytosis; Barrier function; Lysosome; Ubiquitin ligase; Ubiquitin; Biology; Chemistry; Cell; Intracellular; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001837269,0.0004370192,0.0001913253,0.0002763923,0.0003005066,0.0004424652,0.0002087991,0.0004581209,0.001662137],"category_scores_gemma":[0.0002044919,0.0001180824,0.0002651711,0.0001822868,0.0002612915,0.0003665974,0.0003624924,0.0002936149,0.0005359304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004229268,"about_ca_system_score_gemma":0.0002416123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004116728,"about_ca_topic_score_gemma":0.0003250005,"domain_scores_codex":[0.9998881,0.00002117179,0.00001054557,0.00002586024,0.00002520181,0.00002919652],"domain_scores_gemma":[0.9998461,0.00001327144,0.00004647729,0.00001474157,0.00003143021,0.00004789067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001996714,0.00004595675,0.001889782,0.00008380684,0.00001624349,0.000266484,0.00001161962,0.0001064759,0.9940065,0.0004113901,0.0001183256,0.002843696],"study_design_scores_gemma":[0.00005551077,0.0006023422,0.04242216,0.00002902434,0.0001114446,0.00434195,0.0001090103,0.003603692,0.928061,0.001272001,0.01937307,0.00001881166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821246,0.009246486,0.004785762,0.000296402,0.00004875872,0.00003225996,0.0002481577,0.0001172511,0.003100319],"genre_scores_gemma":[0.9949987,0.001793406,0.001676537,0.00003986682,0.00001463911,0.000009607774,0.0001455383,0.000008626787,0.001312988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001662137,"threshold_uncertainty_score":0.005560398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00652208476038423,"score_gpt":0.2124246663474719,"score_spread":0.2059025815870876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}