{"id":"W2019693087","doi":"10.1159/000341450","title":"Ubiquitin E3 Ligase A20 Contributes to Maintaining Epithelial Barrier Function","year":2012,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Science and Technology Commission of Shanghai Municipality; Institute of Engineering Research, Seoul National University; National Natural Science Foundation of China","keywords":"Cell biology; Endosome; Endocytic cycle; Endocytosis; Barrier function; Lysosome; Ubiquitin ligase; Ubiquitin; Biology; Chemistry; Cell; Intracellular; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003118979,0.0002534495,0.0002234119,0.00003371205,0.0001745861,0.00001753479,0.0001558186,0.0003942979,0.00006349452],"category_scores_gemma":[0.0001484414,0.0002459961,0.00009769105,0.00008091189,0.0002236044,0.000005633948,0.0002140988,0.0001718883,0.00004323204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001768207,"about_ca_system_score_gemma":0.00005319212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003333052,"about_ca_topic_score_gemma":3.609218e-7,"domain_scores_codex":[0.998634,0.00006979631,0.000219661,0.0004700001,0.00007691661,0.0005296541],"domain_scores_gemma":[0.9992056,0.00002626008,0.00007918166,0.0003605112,0.00007422709,0.0002542554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002503816,0.00006019458,0.001042814,0.0000366836,0.00007553325,0.000002416525,0.00003486998,0.000007381921,0.9970273,0.0001471301,0.0008670639,0.0004481825],"study_design_scores_gemma":[0.0004878968,0.0001592915,0.0006823816,0.000023641,0.00004508389,0.00001548165,0.0001066435,0.000009129595,0.98624,0.0002157242,0.01172879,0.0002859186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950468,0.002199355,0.001851981,0.00009486096,0.0003064814,0.0001391419,0.0000581979,0.00003107123,0.0002721077],"genre_scores_gemma":[0.9963429,0.00003336304,0.0002028228,0.001061695,0.001279417,0.00003724239,0.0004293362,0.00002861461,0.0005846086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01086173,"threshold_uncertainty_score":0.9999992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00652208476038423,"score_gpt":0.2124246663474719,"score_spread":0.2059025815870876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}