{"id":"W2019781558","doi":"10.1016/j.gene.2008.05.009","title":"DNA demethylation induced by the methyl-CpG-binding domain protein MBD3","year":2008,"lang":"en","type":"article","venue":"Gene","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"DNA methylation; Biology; DNA demethylation; Promoter; Methylated DNA immunoprecipitation; Methylation; Molecular biology; Epigenetics of physical exercise; CpG site; Demethylation; Repressor; Epigenomics; DNA binding site; Bisulfite sequencing; Genetics; DNA; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001134662,0.00021424,0.0001937921,0.0001990554,0.0002613071,0.0002587859,0.0002147423,0.0002189776,0.001388751],"category_scores_gemma":[0.0001932305,0.0001566295,0.0002073395,0.0001323311,0.0002796945,0.0001213044,0.0002661978,0.0004947727,0.0004823727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005959822,"about_ca_system_score_gemma":0.0002274672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001892322,"about_ca_topic_score_gemma":0.002279578,"domain_scores_codex":[0.9999254,0.00001027964,0.000003407384,0.00001779096,0.00002041537,0.00002274513],"domain_scores_gemma":[0.9999036,0.00002521061,0.0000209971,0.00001573389,0.000009962696,0.0000245014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001573799,0.000007565293,0.0002771264,0.0000183404,0.000004752692,0.00005079482,0.000006818098,0.00003893943,0.9984576,0.0001755026,0.00009729628,0.0007079492],"study_design_scores_gemma":[0.00001529598,0.00002998579,0.004957495,0.000002914837,0.000006054995,0.0001450282,0.00001858355,0.0007574449,0.9916906,0.0001280345,0.002245345,0.000003253113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887251,0.003302434,0.004492207,0.0004352411,0.00008250115,0.00001337578,0.0007107945,0.0002151604,0.002023142],"genre_scores_gemma":[0.9951681,0.0004402459,0.001165485,0.00007221017,0.000008825106,0.000009618138,0.0008427728,0.0000382098,0.002254574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001892322,"threshold_uncertainty_score":0.004645884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02112684128459844,"score_gpt":0.2513310348602687,"score_spread":0.2302041935756703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}