{"id":"W2019794292","doi":"10.1016/s0041-0101(03)00133-8","title":"A rapid assay for the brevetoxin group of sodium channel activators based on fluorescence monitoring of synaptoneurosomal membrane potential","year":2003,"lang":"en","type":"article","venue":"Toxicon","topic":"Marine Toxins and Detection Methods","field":"Environmental Science","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"Simon Fraser University; Mote Marine Laboratory and Aquarium; Canadian Food Inspection Agency","keywords":"Sodium channel; Context (archaeology); Veratridine; Membrane potential; Chemistry; Depolarization; Biochemistry; Rhodamine 123; Pharmacology; Cytotoxicity; Biology; Biophysics; Sodium; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008288859,0.001251549,0.0007192629,0.0009882235,0.0005612251,0.0005229075,0.001183063,0.001354795,0.001239472],"category_scores_gemma":[0.0008449137,0.0004958589,0.0004374899,0.0004865959,0.0006930121,0.000659515,0.0009486552,0.001901347,0.001047848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005684215,"about_ca_system_score_gemma":0.0008192441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009041039,"about_ca_topic_score_gemma":0.001605797,"domain_scores_codex":[0.9993819,0.0001320967,0.00003109439,0.0001391742,0.0002216762,0.00009401421],"domain_scores_gemma":[0.9991643,0.0003058215,0.00009735549,0.00009331032,0.0001827677,0.0001565359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009183313,0.00003043585,0.0001732986,0.00003100316,0.000007170332,0.00001441551,0.00001936084,0.00003034334,0.9971066,0.0001619642,0.00006042429,0.002273111],"study_design_scores_gemma":[0.00002337884,0.0003149345,0.001411012,0.000008923879,0.00001551614,0.0001653183,0.00001919877,0.001169918,0.9957118,0.0001296392,0.001020599,0.000009721206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4802237,0.005929707,0.5037909,0.0004533512,0.0002780968,0.00117694,0.0008556578,0.002007589,0.005283959],"genre_scores_gemma":[0.712239,0.004245514,0.2640385,0.0005049887,0.000076702,0.001557427,0.003196802,0.0001360112,0.01400507],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001354795,"threshold_uncertainty_score":0.004383624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01912351405044471,"score_gpt":0.2531079544457587,"score_spread":0.233984440395314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}