{"id":"W2019845984","doi":"10.1016/j.vaccine.2009.12.059","title":"Engineering filamentous phage carriers to improve focusing of antibody responses against peptides","year":2010,"lang":"en","type":"article","venue":"Vaccine","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Simon Fraser University","keywords":"Filamentous bacteriophage; Phagemid; Phage display; Bacteriophage; Hapten; Immunogenicity; Epitope; Peptide; Recombinant DNA; Biology; Peptide library; Molecular biology; Antibody; Chemistry; Peptide sequence; Virology; Biochemistry; Escherichia coli; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002772107,0.000170879,0.0003444217,0.0002793774,0.00006115327,0.00001682244,0.0001344852,0.00007468991,0.0001928162],"category_scores_gemma":[0.0005098103,0.0001372433,0.0001097479,0.0002791918,0.00001502051,0.00006025936,0.0001102832,0.0003318109,0.00004207461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002332374,"about_ca_system_score_gemma":0.0001042202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001750107,"about_ca_topic_score_gemma":0.0000202055,"domain_scores_codex":[0.998759,0.00001686632,0.0002905408,0.000256121,0.0003041093,0.0003734152],"domain_scores_gemma":[0.9990227,0.0001500805,0.0000518178,0.0003260095,0.0001467973,0.0003026495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007649833,0.00005989878,0.01284159,0.0001618825,0.00006385795,0.00009409464,0.0001878821,0.00001376817,0.9778755,0.00007357887,0.0006688564,0.007194102],"study_design_scores_gemma":[0.001348256,0.0006027872,0.1026906,0.0001766615,0.00004452769,0.00006365854,0.00008761773,0.0007442134,0.8550248,0.00001098899,0.03898051,0.0002254442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968622,0.000150776,0.00008342084,0.001145146,0.0002933644,0.0003346409,0.00005014073,0.00004836602,0.0010319],"genre_scores_gemma":[0.9917216,0.00005260262,0.003325294,0.0002385589,0.0004251459,0.000009685597,0.00002728544,0.00003074146,0.004169111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1228508,"threshold_uncertainty_score":0.559662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01141030482100748,"score_gpt":0.3113270706026744,"score_spread":0.2999167657816669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}