{"id":"W2019859148","doi":"10.1016/j.bpj.2011.11.2135","title":"Structure and Dynamics Provides Direct Insight into Proapelin Processing","year":2012,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Apelin; Peptide; Biochemistry; Protease; Proprotein convertase; Chemistry; Cleavage (geology); G protein-coupled receptor; Furin; Signal peptide; Biology; Receptor; Peptide sequence; Enzyme; Gene; LDL receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009182667,0.0002430527,0.0001503964,0.000132584,0.000285371,0.0006245706,0.0002231364,0.0004106414,0.002115601],"category_scores_gemma":[0.0003407859,0.0001614106,0.0001418818,0.0001279661,0.000268295,0.001198692,0.0002296575,0.0008640277,0.0004634143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002352852,"about_ca_system_score_gemma":0.0001279007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002895844,"about_ca_topic_score_gemma":0.0002729172,"domain_scores_codex":[0.9999669,0.000002901488,0.000001809509,0.00001217827,0.000008744646,0.000007516605],"domain_scores_gemma":[0.9998958,0.00003551088,0.00001785291,0.00001699138,0.00001226324,0.00002149833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003983123,0.00006643238,0.002207327,0.00007988994,0.00002067689,0.0006530393,0.0002286478,0.002102008,0.9714835,0.009633465,0.001069381,0.01205724],"study_design_scores_gemma":[0.0001251668,0.0003286288,0.035482,0.00003785374,0.00005398501,0.002496379,0.0005488688,0.1259217,0.7831304,0.02855326,0.0232195,0.0001021763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9704201,0.0007277385,0.01773111,0.00116978,0.0001409387,0.00001501156,0.0004237347,0.0001774529,0.009194276],"genre_scores_gemma":[0.9895216,0.0005938997,0.006764886,0.0001794815,0.00004120327,0.0000143215,0.0006289592,0.00004136576,0.002214355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002115601,"threshold_uncertainty_score":0.007077396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526588447556004,"score_gpt":0.3113959146565424,"score_spread":0.2961300301809823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}