{"id":"W2019905166","doi":"10.1089/biores.2012.0275","title":"Human rElafin Inhibits HIV-1 Replication in Its Natural Target Cells","year":2013,"lang":"en","type":"article","venue":"BioResearch open access","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"","keywords":"Enfuvirtide; Elafin; Gp41; Virology; Viral replication; Amprenavir; Biology; Entry inhibitor; Darunavir; Saquinavir; Maraviroc; Viral entry; Virus; Protease; Immunology; Human immunodeficiency virus (HIV); Viral load; Biochemistry; Epitope; Enzyme; HIV-1 protease; Antiretroviral therapy; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0008408554,0.0001801349,0.0002601879,0.0003469482,0.0003175997,0.0006672001,0.002390075,0.000177563,0.007991918],"category_scores_gemma":[0.0002393235,0.0001427993,0.00004970061,0.0005458949,0.0001872842,0.001518189,0.002071476,0.0006466009,0.02366186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001783597,"about_ca_system_score_gemma":0.0001868749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003499757,"about_ca_topic_score_gemma":0.0003455406,"domain_scores_codex":[0.9975146,0.00050414,0.0003336291,0.0006811411,0.0001313307,0.0008351693],"domain_scores_gemma":[0.9987049,0.0001121957,0.00007313945,0.0007807407,0.0002281232,0.000100871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000979777,0.0004816357,0.02603915,0.00002827932,0.00006984053,0.0000252728,0.0001273027,0.000001607608,0.7764224,0.0006245786,0.1908853,0.005196554],"study_design_scores_gemma":[0.002800465,0.000190583,0.2198008,0.00005576506,0.000003581151,0.000008282505,0.00007808179,0.00001827505,0.7400312,0.0004469552,0.03631121,0.0002547604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793681,0.001351254,0.000003576741,0.003187863,0.0001215438,0.002982735,0.0001199326,0.00004449564,0.01282053],"genre_scores_gemma":[0.9578086,0.00007590408,0.00007401021,0.00009512492,0.00002224169,0.0009111243,0.0007890857,0.00002111821,0.04020279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1937616,"threshold_uncertainty_score":0.9929149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07119241346599076,"score_gpt":0.4155184836567819,"score_spread":0.3443260701907911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}