{"id":"W2019929645","doi":"10.1085/jgp.20028676","title":"Fine Gating Properties of Channels Responsible for Persistent Sodium Current Generation in Entorhinal Cortex Neurons","year":2002,"lang":"en","type":"article","venue":"The Journal of General Physiology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Depolarization; Gating; Entorhinal cortex; Electrophysiology; Time constant; Conductance; Chemistry; Sodium channel; Patch clamp; Biophysics; Neuroscience; Physics; Hippocampus; Biology; Sodium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002840431,0.00008245966,0.0001434144,0.00006389563,0.00006138573,0.000004868417,0.0001029389,0.00005044329,0.00001670616],"category_scores_gemma":[0.00007600791,0.00005481912,0.0001182795,0.00005669913,0.00005694102,0.000006760412,0.00002807901,0.0000811702,8.076646e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001417697,"about_ca_system_score_gemma":0.00003403764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004880052,"about_ca_topic_score_gemma":0.000008322772,"domain_scores_codex":[0.9992133,0.0001657311,0.0003197821,0.00009036271,0.00008359089,0.0001272475],"domain_scores_gemma":[0.9994183,0.00001061926,0.0002569554,0.0001006865,0.000187142,0.00002627612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004533664,0.00007011161,0.00002451211,0.00001507445,0.00002005397,9.980141e-8,0.0001982413,0.02274155,0.9734616,0.00003136893,0.002027979,0.0009560382],"study_design_scores_gemma":[0.001424651,0.002040597,0.002020773,0.00003305866,0.0000447747,0.00005048628,0.0001308664,0.1105887,0.8795929,0.0001006862,0.003836014,0.000136556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964338,0.001644527,0.0004396548,0.0004982354,0.0008354813,0.0001311766,0.000002850911,0.00000124164,0.00001303237],"genre_scores_gemma":[0.9978237,0.0002199966,0.00009146397,0.00006123239,0.001426017,0.000005442445,0.00001417628,0.000008005639,0.0003500003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09386872,"threshold_uncertainty_score":0.2235459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05662598719264068,"score_gpt":0.2637040956415423,"score_spread":0.2070781084489017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}