{"id":"W2019972202","doi":"10.1016/s0042-6822(03)00242-3","title":"Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection","year":2003,"lang":"en","type":"article","venue":"Virology","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital","funders":"","keywords":"Biology; Caspase; Cytochrome c; Apoptosis; Bcl-xL; Programmed cell death; Viability assay; Cytopathic effect; Virus; Intrinsic apoptosis; Mitochondrion; Cell biology; Molecular biology; Caspase 3; Virology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003538089,0.0004674325,0.0005170166,0.0003408226,0.0004333472,0.0006756152,0.0003379356,0.0004408669,0.001340804],"category_scores_gemma":[0.000391229,0.0002380634,0.0003880663,0.0003054176,0.0004489614,0.0005992693,0.0002971891,0.001669174,0.0003344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006434157,"about_ca_system_score_gemma":0.0004054939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008154523,"about_ca_topic_score_gemma":0.001143118,"domain_scores_codex":[0.9995897,0.00006654576,0.00004289287,0.00003398458,0.00008008385,0.0001868143],"domain_scores_gemma":[0.9994022,0.0001881658,0.00009785662,0.00009023026,0.00004555958,0.0001761312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002242713,0.0003614361,0.0003923068,0.00006026881,0.00001863956,0.0001240642,0.0000481396,0.000129875,0.9941767,0.0002937168,0.0001513436,0.002000872],"study_design_scores_gemma":[0.0001215054,0.0008715387,0.003163618,0.000007591631,0.00002048111,0.0002226332,0.00005765275,0.001104541,0.9934826,0.00008461477,0.0008558488,0.00000721313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971486,0.001032826,0.0006954973,0.00009804773,0.00004866902,0.00001489764,0.0001135942,0.00006725189,0.0007805575],"genre_scores_gemma":[0.9974483,0.0003500122,0.0006323868,0.00003746203,0.00002301845,0.00002206263,0.000290139,0.00001350935,0.001183005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001340804,"threshold_uncertainty_score":0.004668355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02233599430090968,"score_gpt":0.2966758133252444,"score_spread":0.2743398190243347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}