{"id":"W2019972202","doi":"10.1016/s0042-6822(03)00242-3","title":"Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection","year":2003,"lang":"en","type":"article","venue":"Virology","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital","funders":"","keywords":"Biology; Caspase; Cytochrome c; Apoptosis; Bcl-xL; Programmed cell death; Viability assay; Cytopathic effect; Virus; Intrinsic apoptosis; Mitochondrion; Cell biology; Molecular biology; Caspase 3; Virology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000272769,0.0001714451,0.0003880778,0.0003094384,0.0002054125,0.00001213399,0.0000269609,0.0003169514,0.00007653808],"category_scores_gemma":[0.0009565933,0.0001527485,0.00007125411,0.0002616454,0.0002208083,0.0002295061,0.00006319256,0.0003942619,0.00001421745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005839191,"about_ca_system_score_gemma":0.00007095659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001313247,"about_ca_topic_score_gemma":0.00006630493,"domain_scores_codex":[0.9986585,0.0002630014,0.0003114421,0.0003432597,0.0001372324,0.0002865358],"domain_scores_gemma":[0.9992403,0.000184911,0.0001246542,0.0002521097,0.00008277411,0.0001152999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005081451,0.0002433496,0.03678308,0.00007557641,0.00008774259,0.00002324261,0.00007162244,0.000009362111,0.9545156,0.0001643501,0.0001543431,0.007363549],"study_design_scores_gemma":[0.006859927,0.002767056,0.5236698,0.0002796076,0.0001332479,0.0004863127,0.00006834686,0.0007289068,0.4562279,0.0002649492,0.008247864,0.0002661186],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972468,0.001112458,0.0002619478,0.0001652604,0.0000898494,0.0004441793,0.000008171814,0.00004614479,0.0006251973],"genre_scores_gemma":[0.9981467,0.001234045,0.0001288212,0.0001772677,0.00003532186,0.00003044338,0.00002448882,0.00002340327,0.0001994975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4982877,"threshold_uncertainty_score":0.6228904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02233599430090968,"score_gpt":0.2966758133252444,"score_spread":0.2743398190243347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}