{"id":"W2019981995","doi":"10.1006/mthe.2001.0412","title":"Targeting Transgene Expression for Cystic Fibrosis Gene Therapy","year":2001,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Energy Harvesting in Wireless Networks","field":"Engineering","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; SickKids Foundation; University of Toronto; Hospital for Sick Children; Canadian Institutes of Health Research","funders":"Medical Research Council; Medical Research Council Canada; Canadian Institutes of Health Research; Hospital for Sick Children; Cystic Fibrosis Foundation","keywords":"Genetic enhancement; Cystic fibrosis; Transgene; Gene expression; Pathology; Viral vector; Biology; Gene delivery; Medicine; Cancer research; Molecular biology; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001673947,0.0002784622,0.000230096,0.00006669673,0.0001131104,0.00005172186,0.0002486219,0.0001571633,0.00005352243],"category_scores_gemma":[0.00001239212,0.0002652745,0.0001449413,0.0001982675,0.0000257526,0.00007870486,0.000008384934,0.0001373247,0.000007463509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003624992,"about_ca_system_score_gemma":0.000009621242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004729828,"about_ca_topic_score_gemma":4.725413e-7,"domain_scores_codex":[0.9987699,0.00005470934,0.0002626499,0.0002827411,0.0001773061,0.0004526876],"domain_scores_gemma":[0.9994072,0.00009441257,0.00003716759,0.000324309,0.00004596009,0.00009098199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005642561,0.0000193216,0.00004061414,0.000008218656,0.0000369316,0.00001068048,0.00009458929,0.3324638,0.6478372,0.00002309215,0.0002106714,0.01919853],"study_design_scores_gemma":[0.0014398,0.0001127546,0.00009806307,0.00005380924,0.000005837251,0.000008277718,0.000009720809,0.07150517,0.8909439,0.0002676056,0.03515818,0.0003968469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5332687,0.01024095,0.4553841,0.00003222652,0.0002399138,0.0002570005,0.000004930708,0.0004127565,0.0001594408],"genre_scores_gemma":[0.9578408,0.004448956,0.03659432,0.0002325285,0.0002981072,0.0002420168,0.00007334459,0.0001881707,0.00008173794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4245721,"threshold_uncertainty_score":0.99998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01185108519409047,"score_gpt":0.2201923596175218,"score_spread":0.2083412744234313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}