{"id":"W2020071485","doi":"10.1006/cyto.2002.0885","title":"IMMUNOSUPPRESSANTS LEFLUNOMIDE AND MYCOPHENOLIC ACID INHIBIT FIBROBLAST IL-6 PRODUCTION BY DISTINCT MECHANISMS","year":2002,"lang":"en","type":"article","venue":"Cytokine","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Nitric oxide; Chemistry; Sodium nitroprusside; Leflunomide; Fibroblast; Mycophenolic acid; Pharmacology; Biochemistry; Transplantation; Biology; Immunology; In vitro; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004311796,0.0001818895,0.0002462746,0.00006300938,0.0001021288,0.00002457483,0.00004084199,0.00006092561,0.0002853512],"category_scores_gemma":[0.00003063206,0.0001437766,0.00005243149,0.000114562,0.00004993456,0.0001214413,0.0000180966,0.0001035497,0.0001348586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000367438,"about_ca_system_score_gemma":0.000005760883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000244025,"about_ca_topic_score_gemma":0.000003457026,"domain_scores_codex":[0.9990652,0.00001924801,0.0002241369,0.0003020285,0.0001798262,0.0002095618],"domain_scores_gemma":[0.9995472,0.00002133765,0.00006591124,0.0002144539,0.00003656753,0.0001144615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004171247,0.0005380045,0.01084851,0.0004577629,0.0003070988,0.0001377944,0.0004901962,0.000005012913,0.9717252,0.0002031466,0.003764303,0.01110585],"study_design_scores_gemma":[0.006013744,0.0009699508,0.07924076,0.001079064,0.000359994,0.001021885,0.00006472031,0.0001641803,0.9043624,0.0004523727,0.005850087,0.0004208032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949436,0.000931645,0.0005047348,0.001379704,0.0001569457,0.0004629883,0.0001696726,0.0001545778,0.001296115],"genre_scores_gemma":[0.9951898,0.0003846523,0.0007455523,0.0001256747,0.00007475571,0.00002531526,0.0001272102,0.00003546604,0.003291524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06839225,"threshold_uncertainty_score":0.586304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01584007592274575,"score_gpt":0.2370688200046322,"score_spread":0.2212287440818864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}