{"id":"W2020071485","doi":"10.1006/cyto.2002.0885","title":"IMMUNOSUPPRESSANTS LEFLUNOMIDE AND MYCOPHENOLIC ACID INHIBIT FIBROBLAST IL-6 PRODUCTION BY DISTINCT MECHANISMS","year":2002,"lang":"en","type":"article","venue":"Cytokine","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Nitric oxide; Chemistry; Sodium nitroprusside; Leflunomide; Fibroblast; Mycophenolic acid; Pharmacology; Biochemistry; Transplantation; Biology; Immunology; In vitro; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003603746,0.0005853834,0.000637166,0.000359502,0.0002672246,0.0005028544,0.0002648255,0.0004757634,0.001564818],"category_scores_gemma":[0.0003302342,0.0002070035,0.0006230075,0.0001593566,0.0003586535,0.0005443191,0.0003726837,0.0009759371,0.0003944248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002484844,"about_ca_system_score_gemma":0.000295473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003037381,"about_ca_topic_score_gemma":0.0005751323,"domain_scores_codex":[0.9995598,0.000123973,0.0000472582,0.00004011264,0.00009780619,0.0001309533],"domain_scores_gemma":[0.9996401,0.0001093865,0.00008245901,0.00004576021,0.00005054038,0.00007169576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002369977,0.0002218747,0.001044822,0.0002055696,0.00003814219,0.0003665382,0.00006752665,0.00007502464,0.9845557,0.0007905842,0.0001799341,0.01008432],"study_design_scores_gemma":[0.0005252436,0.002316754,0.03378822,0.00004601383,0.0001160823,0.001420598,0.0001977114,0.000883594,0.954527,0.0004368994,0.005726675,0.00001530147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9612737,0.02406558,0.004873496,0.0007890618,0.0002983465,0.0001717754,0.0005083488,0.00008712421,0.007932486],"genre_scores_gemma":[0.9843644,0.00786339,0.002880054,0.0002967452,0.0001829487,0.000170018,0.0003785083,0.00001510122,0.003848787],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001564818,"threshold_uncertainty_score":0.005234897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01584007592274575,"score_gpt":0.2370688200046322,"score_spread":0.2212287440818864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}