{"id":"W2020118719","doi":"10.1073/pnas.0305943101","title":"A deoxyribozyme that harnesses light to repair thymine dimers in DNA","year":2003,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Photolyase; Pyrimidine dimer; Thymine; Deoxyribozyme; Guanine; DNA; Nucleic acid; Chemistry; Biochemistry; Oligonucleotide; Stereochemistry; Nucleotide; Photochemistry; DNA repair; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001458765,0.0002744793,0.0002583431,0.0001050859,0.00008311156,0.0002821704,0.0001960024,0.0003091343,0.0003851562],"category_scores_gemma":[0.0001501569,0.0001058371,0.000168946,0.00009936323,0.0001871951,0.0001122504,0.0001226507,0.0003177956,0.000262806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001860458,"about_ca_system_score_gemma":0.00008478727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000162574,"about_ca_topic_score_gemma":0.0002731135,"domain_scores_codex":[0.9998797,0.00002835625,0.000009108743,0.00003333079,0.00003030801,0.00001921602],"domain_scores_gemma":[0.9999003,0.00003492696,0.00002348921,0.00001257501,0.00001050977,0.00001815353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001252105,0.000005986288,0.0001034637,0.00001419457,0.000001920973,0.00002452553,0.000004042525,0.00005399587,0.9989354,0.00006549485,0.000006211927,0.0007723131],"study_design_scores_gemma":[0.000003425167,0.00007407372,0.0005548025,0.000001884941,0.000005199805,0.0001473531,0.00000418787,0.0006746436,0.9975424,0.00002268432,0.0009676411,0.000001657162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775393,0.001504642,0.01862212,0.00005119421,0.00004396745,0.00005166521,0.0001663085,0.0001188297,0.00190208],"genre_scores_gemma":[0.9836516,0.000690859,0.01296372,0.00004495649,0.00000776011,0.00002515763,0.0004691262,0.00002772453,0.002119133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003851562,"threshold_uncertainty_score":0.001349807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02517982701035674,"score_gpt":0.305527027289047,"score_spread":0.2803472002786903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}