{"id":"W2020138546","doi":"10.1038/cmi.2012.37","title":"A novel T cell-based vaccine capable of stimulating long-term functional CTL memory against B16 melanoma via CD40L signaling","year":2012,"lang":"en","type":"article","venue":"Cellular and Molecular Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; University of Saskatchewan; Saskatchewan Cancer Agency","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation","keywords":"CTL*; Melanoma; CD40; Term (time); Immunology; Medicine; Cancer research; Biology; Virology; Immune system; Cytotoxic T cell; Genetics; CD8","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116424,0.0004514371,0.0002724773,0.000213502,0.0001627828,0.0004127076,0.0002717551,0.0005138747,0.001218622],"category_scores_gemma":[0.00009932051,0.0001549768,0.0002381924,0.0001077412,0.0001999454,0.0003621142,0.0002182943,0.0008425339,0.000438277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003362112,"about_ca_system_score_gemma":0.0003736474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003847241,"about_ca_topic_score_gemma":0.0004123977,"domain_scores_codex":[0.9999169,0.00001109063,0.000005098954,0.00001692523,0.0000182858,0.00003171503],"domain_scores_gemma":[0.9999626,0.000006017176,0.000007078886,0.000003591294,0.000006372374,0.00001448117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001922106,0.0001563201,0.00009045318,0.00006709818,0.000007810632,0.00009400962,0.00001674058,0.0003399432,0.99198,0.0003465551,0.0002139746,0.006494984],"study_design_scores_gemma":[0.000311234,0.002024054,0.0006901415,0.0000112004,0.00006061941,0.0004611563,0.0000224539,0.004451117,0.9830856,0.0003003735,0.008570201,0.00001182726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779834,0.003129613,0.01414887,0.0005830819,0.0002281926,0.0001607272,0.0002727219,0.0003307313,0.003162661],"genre_scores_gemma":[0.9893622,0.00100603,0.005818054,0.0001767871,0.00004691433,0.0000945043,0.0003467604,0.00001776889,0.00313099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001218622,"threshold_uncertainty_score":0.00407666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01845580264347052,"score_gpt":0.2565204328658132,"score_spread":0.2380646302223426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}