{"id":"W2020162055","doi":"10.1074/jbc.m101932200","title":"Characterization of Recombinant HPV6 and 11 E1 Helicases","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"Helicase; ATP hydrolysis; dnaB helicase; DNA; Transactivation; Amino acid; Recombinant DNA; Biology; Enzyme; Biochemistry; ATPase; DNA replication; DNA-binding domain; Mutant; Bovine papillomavirus; Chemistry; Molecular biology; Gene; Gene expression; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001018067,0.00009192039,0.0001661204,0.00001319732,0.0000339706,0.000009656449,0.00009314884,0.0001473402,0.00009266958],"category_scores_gemma":[0.0001310534,0.00006315491,0.0001029325,0.00004701694,0.00008029067,0.000004283131,0.00005977015,0.00006729666,4.875315e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005149688,"about_ca_system_score_gemma":0.00002522529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002070929,"about_ca_topic_score_gemma":2.821549e-7,"domain_scores_codex":[0.9993818,0.00002748763,0.0002942808,0.0001223524,0.00007075856,0.0001033624],"domain_scores_gemma":[0.9993832,0.00001149474,0.0002920114,0.0001014355,0.0001184307,0.00009346742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001491802,0.0001172867,0.02670483,0.00001937434,0.00001873716,0.00001074001,0.000004350534,0.000001745555,0.9712818,0.000002651118,0.0003227463,0.001366515],"study_design_scores_gemma":[0.0003968589,0.0004681813,0.0181106,0.00003804686,0.000012313,0.0003612709,0.0000263295,0.000004072836,0.9636434,0.00008863811,0.01675616,0.00009416071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987421,0.000635943,0.0001741512,0.00007624917,0.0001153842,0.00003092576,0.000007902264,0.000002954711,0.0002143721],"genre_scores_gemma":[0.9965988,0.002750581,0.00006619244,0.00008936719,0.000255898,0.000001707075,0.00002801595,0.000005024564,0.0002044051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01643342,"threshold_uncertainty_score":0.2575382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01609286771620239,"score_gpt":0.2564923691298228,"score_spread":0.2403995014136204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}