{"id":"W2020276240","doi":"10.1002/hep.27586","title":"Adding pegylated interferon to entecavir for hepatitis B e antigen–positive chronic hepatitis B: A multicenter randomized trial (ARES study)","year":2014,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Sociale en Geesteswetenschappen, NWO; NIH Clinical Center; Ruijin Hospital; Gilead Sciences; Virgo Consortium; Fudan University; Santen; Bristol-Myers Squibb","keywords":"Medicine; Entecavir; HBeAg; Internal medicine; Gastroenterology; Pegylated interferon; Hepatitis B; Randomized controlled trial; Odds ratio; Seroconversion; Combination therapy; Hepatitis B virus; Confidence interval; Hepatology; Immunology; HBsAg; Chronic hepatitis; Lamivudine; Virus; Ribavirin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005432526,0.001776718,0.002574003,0.0003614334,0.0003486352,0.001297044,0.0007822911,0.001709736,0.004227067],"category_scores_gemma":[0.002742372,0.0006117958,0.002860529,0.00042389,0.001153455,0.0008018884,0.0004278178,0.002544732,0.0005754116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004287031,"about_ca_system_score_gemma":0.001033124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000463826,"about_ca_topic_score_gemma":0.0009653139,"domain_scores_codex":[0.9976842,0.001761172,0.0001249428,0.0002015725,0.0001008484,0.0001271387],"domain_scores_gemma":[0.9977603,0.0006485206,0.0006741702,0.0001949886,0.0001732446,0.0005487178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9851578,0.002849523,0.0008814594,0.0005579411,0.001215183,0.00001855951,0.0000335539,0.0001026334,0.001363278,0.0000621736,0.0003720493,0.007385974],"study_design_scores_gemma":[0.9516023,0.0448404,0.001684737,0.00005219274,0.0008653251,0.00002724613,0.00001405022,0.000166945,0.0002830398,0.00005589706,0.0003998228,0.000008014557],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884144,0.005308314,0.000457998,0.001046624,0.000594051,0.002415547,0.0004701114,0.00007328681,0.001219527],"genre_scores_gemma":[0.9852763,0.00415454,0.001930153,0.001470685,0.001179609,0.003300701,0.000903361,0.00002277994,0.001761898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005432526,"threshold_uncertainty_score":0.02873033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01980793149219631,"score_gpt":0.3172065694049382,"score_spread":0.2973986379127419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}