{"id":"W2020276240","doi":"10.1002/hep.27586","title":"Adding pegylated interferon to entecavir for hepatitis B e antigen–positive chronic hepatitis B: A multicenter randomized trial (ARES study)","year":2014,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Sociale en Geesteswetenschappen, NWO; NIH Clinical Center; Ruijin Hospital; Gilead Sciences; Virgo Consortium; Fudan University; Santen; Bristol-Myers Squibb","keywords":"Medicine; Entecavir; HBeAg; Internal medicine; Gastroenterology; Pegylated interferon; Hepatitis B; Randomized controlled trial; Odds ratio; Seroconversion; Combination therapy; Hepatitis B virus; Confidence interval; Hepatology; Immunology; HBsAg; Chronic hepatitis; Lamivudine; Virus; Ribavirin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009971407,0.0005412658,0.002413564,0.0004566225,0.00030708,0.00004629433,0.0002373451,0.0002488352,0.0002792293],"category_scores_gemma":[0.003223778,0.0004771909,0.0004879691,0.0002905547,0.0002796296,0.0001201728,0.0002548078,0.0003330862,0.0002358274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004979344,"about_ca_system_score_gemma":0.0001654563,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01330158,"about_ca_topic_score_gemma":0.03397693,"domain_scores_codex":[0.9956231,0.0009568764,0.001188591,0.0009335661,0.0003637632,0.0009340858],"domain_scores_gemma":[0.9966974,0.001630746,0.000303683,0.0005758264,0.0004871148,0.0003051942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5400491,0.0010089,0.4382931,0.0001411684,0.001385137,0.000129024,0.003701317,0.000002911851,0.0008168207,0.0003480121,0.00315757,0.0109669],"study_design_scores_gemma":[0.9309031,0.01626025,0.02042147,0.0004438029,0.0008888519,0.00005542967,0.00009366609,0.01232781,0.002535696,0.00008416663,0.01528492,0.0007007902],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9748412,0.0003526055,0.009174238,0.001270041,0.001660891,0.01157786,0.0001116582,0.0002556064,0.0007558721],"genre_scores_gemma":[0.992084,0.0005031312,0.001630249,0.001375508,0.00067172,0.003217046,0.0001216385,0.0000906888,0.0003059815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4178716,"threshold_uncertainty_score":0.999768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01980793149219631,"score_gpt":0.3172065694049382,"score_spread":0.2973986379127419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}