{"id":"W2020284420","doi":"10.1002/em.20111","title":"Mutator phenotype in cancer: Timing and perspectives","year":2005,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Phenotype; Genetics; Mutagen; Cancer; Cancer cell; Mutation; Cell division; Gene; DNA repair; DNA; DNA replication; Cancer research; Cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009649387,0.001149781,0.002081711,0.002188592,0.0003638647,0.001160835,0.001570597,0.001985011,0.001727452],"category_scores_gemma":[0.0009465845,0.0003983763,0.0004191388,0.002407921,0.00172573,0.002361354,0.0007041358,0.002599093,0.002123327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0011671,"about_ca_system_score_gemma":0.0008374893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001220853,"about_ca_topic_score_gemma":0.001593946,"domain_scores_codex":[0.9997398,0.00004683626,0.00003483527,0.00005825937,0.00009674619,0.00002348044],"domain_scores_gemma":[0.9993801,0.0003326133,0.00006592333,0.00002506786,0.0001405927,0.00005577217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001283608,0.00008835766,0.0004069642,0.008656802,0.0000578156,0.0005803038,0.00008849149,0.0008159969,0.003060708,0.01463608,0.02668945,0.9447906],"study_design_scores_gemma":[0.00001948969,0.0001457917,0.001140038,0.002043935,0.00005901621,0.002916698,0.00009259026,0.0001435882,0.001161015,0.008382289,0.9838659,0.00002971778],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007879597,0.9986808,0.0001253051,0.0002667629,0.0001961152,0.000001487807,0.000004901003,0.000005155704,0.0006407738],"genre_scores_gemma":[0.0006581885,0.998325,0.000133289,0.0002370801,0.0002108797,0.00000341621,0.000007444985,0.000001112742,0.0004235149],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002188592,"threshold_uncertainty_score":0.008467972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01801648320139104,"score_gpt":0.273705940647145,"score_spread":0.255689457445754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}