{"id":"W2020342822","doi":"10.1385/cbb:47:1:1","title":"Role of receptor and nonreceptor protein tyrosine kinases in H2O2-induced PKB and ERK1/2 signaling","year":2007,"lang":"en","type":"review","venue":"Cell Biochemistry and Biophysics","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Protein kinase B; Cell biology; Kinase; Signal transduction; Receptor tyrosine kinase; MAPK/ERK pathway; Tyrosine kinase; Receptor Protein-Tyrosine Kinases; Reactive oxygen species; Biology; Cancer research; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002108051,0.0004102765,0.001211511,0.00008974504,0.00003801489,0.00001935652,0.00006993789,0.0004518922,0.00001422728],"category_scores_gemma":[0.00007006693,0.0003309253,0.0001222828,0.0003000805,0.0001417694,0.00003168823,0.0000827444,0.0003976674,0.000003573878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003447829,"about_ca_system_score_gemma":0.0001205839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002341872,"about_ca_topic_score_gemma":2.845599e-7,"domain_scores_codex":[0.9986177,0.00003545292,0.0004462654,0.0004820777,0.0001541864,0.0002642813],"domain_scores_gemma":[0.9991159,0.0001530791,0.0002562193,0.0002384369,0.00006565807,0.0001706577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000467298,0.0001248882,0.00001448636,0.02871532,0.00003211417,0.000009571477,0.00002658621,6.795367e-9,0.6745,0.000002658871,0.00001325437,0.2965143],"study_design_scores_gemma":[0.000760845,0.0002195935,0.000003468287,0.01318823,0.000365653,0.0000256633,0.00009022456,0.000002776157,0.9506032,0.00001734599,0.03436944,0.0003534911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3524237,0.6468062,8.37403e-7,0.000006229301,0.00002116889,0.0004689015,0.00003996787,0.00001251844,0.0002204572],"genre_scores_gemma":[0.0541943,0.9442412,0.000452995,0.00002421073,0.0004202587,0.00003695202,0.0001721228,0.00004794032,0.0004100595],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2982294,"threshold_uncertainty_score":0.9999143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02331453659687179,"score_gpt":0.285819237399406,"score_spread":0.2625047008025342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}