{"id":"W2020426566","doi":"10.1139/o05-043","title":"Caught in conspiracy: cooperation between DNA methylation and histone H3K9 methylation in the establishment and maintenance of heterochromatin","year":2005,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Research UK","keywords":"Epigenomics; Histone methylation; Biology; EZH2; DNA methylation; Chromatin; Heterochromatin; Epigenetics of physical exercise; Histone code; Histone; Heterochromatin protein 1; Methylation; Genetics; Chromatin remodeling; Cell biology; DNA; Gene expression; Gene; Nucleosome","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007271365,0.0002813167,0.0006054632,0.00008728197,0.00004755742,0.00002124555,0.0001157847,0.0006024698,0.00000388231],"category_scores_gemma":[0.0001075433,0.000219572,0.00005674793,0.0001351561,0.0002053847,0.000006910599,0.0000889285,0.0001885602,3.064562e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003098631,"about_ca_system_score_gemma":0.00007919391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003145252,"about_ca_topic_score_gemma":0.00005587032,"domain_scores_codex":[0.9982744,0.0003169533,0.0006377054,0.0005122299,0.00006622858,0.0001924699],"domain_scores_gemma":[0.9991765,0.0001355554,0.0003502965,0.0002476544,0.00004515699,0.00004480504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002428212,0.00007320617,0.0007016748,0.002596065,0.00003838857,0.000001508676,0.0001609821,0.000004457198,0.3457753,0.00004432756,0.00002869737,0.6505511],"study_design_scores_gemma":[0.001360999,0.0003402341,0.0008074834,0.0009716087,0.0002800915,0.00001550551,0.0001202967,0.00004218285,0.3079699,0.0001744341,0.6871617,0.0007555133],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2072934,0.7918873,0.0001160882,0.00005311887,0.00002540367,0.0003614553,0.00005952891,0.000002384796,0.0002012872],"genre_scores_gemma":[0.2686333,0.7300537,0.0001998466,0.00001660923,0.00009606425,0.00004305252,0.0008701065,0.00001206488,0.00007519498],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6871331,"threshold_uncertainty_score":0.8953885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02317897413492153,"score_gpt":0.3155619668806465,"score_spread":0.2923829927457249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}