{"id":"W2020426566","doi":"10.1139/o05-043","title":"Caught in conspiracy: cooperation between DNA methylation and histone H3K9 methylation in the establishment and maintenance of heterochromatin","year":2005,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Research UK","keywords":"Epigenomics; Histone methylation; Biology; EZH2; DNA methylation; Chromatin; Heterochromatin; Epigenetics of physical exercise; Histone code; Histone; Heterochromatin protein 1; Methylation; Genetics; Chromatin remodeling; Cell biology; DNA; Gene expression; Gene; Nucleosome","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002651502,0.0006860001,0.0011222,0.001203165,0.0002933429,0.00087012,0.0007725015,0.001091173,0.00269654],"category_scores_gemma":[0.0002441332,0.0002139769,0.0002280896,0.00153058,0.0004320312,0.001322597,0.0005266533,0.0009712203,0.004087037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006659029,"about_ca_system_score_gemma":0.0005958754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008413466,"about_ca_topic_score_gemma":0.001446814,"domain_scores_codex":[0.9998796,0.00001483812,0.00001109912,0.00003142398,0.00004957542,0.00001344481],"domain_scores_gemma":[0.9999117,0.00002143705,0.00001576284,0.000003409509,0.0000327309,0.00001493654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007238478,0.00003140794,0.0002463721,0.005405134,0.00005260427,0.0007354869,0.0001039675,0.0002623928,0.01348339,0.00591357,0.02090555,0.9527877],"study_design_scores_gemma":[0.000010241,0.00006618274,0.001048734,0.000843655,0.00004850393,0.00329612,0.0001161855,0.00007579731,0.003286416,0.003191486,0.9880001,0.00001671507],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004557504,0.9953927,0.0005062746,0.0002554173,0.0002968755,0.000003916038,0.00001547493,0.00001629743,0.003057315],"genre_scores_gemma":[0.002518568,0.9923503,0.0005792764,0.0002855447,0.0001599225,0.000006562308,0.00004253343,0.000003551181,0.004053735],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00269654,"threshold_uncertainty_score":0.009020865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02317897413492153,"score_gpt":0.3155619668806465,"score_spread":0.2923829927457249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}