{"id":"W2020521224","doi":"10.1002/embj.201386386","title":"E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis","year":2014,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"SLAC National Accelerator Laboratory; Pacific Northwest National Laboratory; Biological and Environmental Research; Howard Hughes Medical Institute; National Institute of Allergy and Infectious Diseases; National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research; U.S. Public Health Service; Office of Science; National Institutes of Health; U.S. Department of Energy","keywords":"Biology; Effector; Shigella; Pathogenesis; Microbiology; Shigella flexneri; Kinase; Virology; Immunology; Cell biology; Genetics; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001392453,0.0003124496,0.0002064097,0.0001478974,0.0002185867,0.0007107229,0.0001528284,0.0003182012,0.001674187],"category_scores_gemma":[0.0001640573,0.0001784575,0.0002000226,0.0001266622,0.000260485,0.0005930965,0.0003154218,0.0005312713,0.0007266724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006190086,"about_ca_system_score_gemma":0.0001542704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003903744,"about_ca_topic_score_gemma":0.0005296498,"domain_scores_codex":[0.9998732,0.0000208097,0.000007503654,0.00002413419,0.0000163221,0.00005799329],"domain_scores_gemma":[0.9999201,0.0000163874,0.00001749165,0.00001215395,0.0000134245,0.00002028599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004001765,0.0000287429,0.0004764547,0.00001369613,0.000003003262,0.00004803395,0.00001765679,0.00008870872,0.9978291,0.0002313961,0.00005532335,0.0008077449],"study_design_scores_gemma":[0.00001265291,0.000070947,0.01392465,0.000003568302,0.000005761065,0.00009387305,0.00007281547,0.001743104,0.9831492,0.0002018773,0.0007150403,0.000006427502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973231,0.0007433479,0.0008642654,0.00007625867,0.00001455284,0.000004430325,0.0001310281,0.00004546801,0.0007975703],"genre_scores_gemma":[0.9981967,0.0001819912,0.0002653119,0.0000226018,0.000003581483,0.0000044688,0.0001976201,0.00001448126,0.001113348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001674187,"threshold_uncertainty_score":0.005600691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008430234554380474,"score_gpt":0.2494589652294133,"score_spread":0.2410287306750328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}